Protein Alignment klhl10 and Klhl38

DIOPT Version :10

• Sequence 1: NP_001015100.2
• Gene: klhl10 / 3354863
• FlyBaseID: FBgn0040038
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: NP_001020179.1
• Gene: Klhl38 / 314996
• RGDID: 1564169
• Length: 580
• Species: Rattus norvegicus
• Alignment Length: 573
• Identity: 139/573 - (24%)
• Similarity: 236/573 - (41%)
• Gaps: 93/573 - (16%)

  Fly    65 SDEALNTLNELREQNLLCDAQISVGEDVFNVHRAIMCSCSSYFRAQFTGFNADTPGCVDGSDAKK 129
            |.:.|..||.||:..:|.|..|..|......||.::.|.|.||||.|.....::      .:||
  Rat    17 SSDLLRQLNGLRQSKILTDVSICSGACEVPCHRNVLASSSPYFRAMFCSHFRES------REAK- 74

  Fly   130 NNNFIHIPGVSSCIMNCVIQYAYLRQTNISESNVHELLICADYVGMVGLVKKCKDYLGRILTPEN 194
                :.:.|:||..:..||.|.|..:.:||.:||..|:..|..:....:.:.|..||...|.|.|
  Rat    75 ----VQLKGISSTTLEQVIAYVYTGEVHISAANVLPLMEAAAMLQYPRMFEACSSYLQSQLAPSN 135

  Fly   195 CVSIMGFARFRFLEDLHLKARNYTLRYFTEVAYRNIDILDMSAEDFYSIISDDELNTREEDHVWK 259
            |:.::..|.....:.|..|||...|.||.||| .:.|:.::...:....:.||:| ..||:.|::
  Rat   136 CLGLVRLAEILSCDSLKKKAREVALTYFPEVA-ASADLKELCVMELRDYLGDDKL-CGEEEKVFE 198

  Fly   260 LCVKWIDRNPESRKRHVAHLMTGVRLGLMTPKCFMEEVKEHPYVLECEAAKPLIVDTFKFMYDLD 324
            ..:.|:..:.::|.|::..|:..|||..:.|..|...:.....:....|.:.::....|.::.|
  Rat   199 ALMAWVKHDLQARWRYMQELLQQVRLQYIHPAFFHHFIASDALLQSSPACQAILEMAKKQIFSL- 262

  Fly   325 FLNPQADELT---TPP----------------------------------LAMPRLP-------- 344
             ..|.|.:..   |||                                  .::.:||
  Rat   263 -YGPSAQDCKLWHTPPRSSYQDFLLLLGGRKDNQQTTRDVLLYSIQTGQWQSLAKLPTRLYKASA 326

  Fly   345 ---HEVIFAIGGWSGGTSKGCIE----TYDTRADRWVTINAEDP--AGPRAYHGTAVLGFKIFSI 400
               |..::.:||.:....||.|.    .:..:.::|   ...:|  |...::..|....| ||||
  Rat   327 VTLHRSVYVLGGMAVREGKGLISCSVYIFSMKLNQW---RMGEPMLAARYSHRSTTHRNF-IFSI 387

  Fly   401 GGY-DGVEYFNTCRVFDAVKKKWNEIAPMHCRRCYVSVTELNGMIYAIGGYD-GHNRLNTVERYN 463
            ||. :|.|...:...:|:::..|..:|.|.....:.:|...:..:|..||.| ..|.:..::.|:
  Rat   388 GGTGEGQELLGSMERYDSIRDVWESMADMPMAVLHPAVAVKDQRLYLFGGEDIMQNPVRLIQVYH 452

  Fly   464 PRTNQWSVIPPMNMQRSDASACTLQERIYATGGFNGQECLDSAEYYDPVTNVWTRIPNMNHRRSG 528
            ...|.|..:....::...|.|..|.|:|...||:..:...     |||.:|.:.:..:|..||..
  Rat   453 ISRNTWYKMETRMIKNVCAPAVVLGEKIIIVGGYTRRILA-----YDPQSNKFVKCADMKDRRMH 512

  Fly   529 VSCVAFRNQLYVIGGFNGTARLSTG---------ERFDPDTQTWHFIREMNHS 572
            .......|:|||.||    .||:|.         :.:||:|.||....::.|:
  Rat   513 HGATVMGNKLYVTGG----RRLTTDCNIEDSASFDCYDPETDTWTSQGQLPHT 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB_POZ	62..>108	CDD:453885	15/42 (36%)
		PHA03098	86..610	CDD:222983	131/552 (24%)
		KELCH repeat	385..428	CDD:276965	13/43 (30%)
		KELCH repeat	432..475	CDD:276965	9/43 (21%)
		KELCH repeat	479..523	CDD:276965	11/43 (26%)
		KELCH repeat	526..571	CDD:276965	15/53 (28%)
		KELCH repeat	573..617	CDD:276965	139/573 (24%)
Klhl38	NP_001020179.1	BTB_POZ	11..139	CDD:453885	41/132 (31%)
		BACK_KLHL38	131..229	CDD:350551	29/99 (29%)
		Kelch 1	284..331		2/46 (4%)
		NanM	286..527	CDD:442289	52/249 (21%)
		KELCH repeat	324..368	CDD:276965	7/46 (15%)
		Kelch 2	333..382		9/51 (18%)
		KELCH repeat	372..416	CDD:276965	13/44 (30%)
		Kelch 3	383..430		14/47 (30%)
		KELCH repeat	420..507	CDD:276965	20/91 (22%)
		Kelch 4	432..478		11/45 (24%)
		Kelch 5	479..520		10/45 (22%)
		Kelch_1	509..559	CDD:396078	16/53 (30%)
		KELCH repeat	510..560	CDD:276965	15/53 (28%)
		Kelch 6	522..572		14/44 (32%)