DRSC/TRiP Functional Genomics Resources

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Protein Alignment klhl10 and Kbtbd11

DIOPT Version :9

Sequence 1:NP_001015100.2 Gene:klhl10 / 3354863 FlyBaseID:FBgn0040038 Length:767 Species:Drosophila melanogaster
Sequence 2:NP_001100796.1 Gene:Kbtbd11 / 306617 RGDID:1563576 Length:633 Species:Rattus norvegicus


Alignment Length:511 Identity:101/511 - (19%)
Similarity:172/511 - (33%) Gaps:134/511 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly    69 LNTLNELRE----------QNLLCDAQISVGEDVFNVHRAIMCSCSSYFRAQFTGFNADTPGCVD 123
            |.:|:||.|          ::...|..|.|.......|:|::.:.|.|||               
  Rat   123 LESLDELGEPVPVPPGVGSEHGEPDLVIEVAGRRLRAHKAVLAARSDYFR--------------- 172

  Fly   124 GSDAKKNNNFIHIPGVSSCIMNCVIQYAYLR-QTNISESNVHELLICADYVGMVGLVKKCKDYLG 187
               |:.:.:.:.:.|||...:..::..||.. ...:...||.|::..|..:.:.|..::..:.:.
  Rat   173 ---ARASRDVLRVQGVSFTALRLLLADAYSGCMAGVRPDNVAEVVAGARRLQLPGAAQRATEAMA 234

  Fly   188 RILTPENCVSIMGFARFRFLEDLHLKARNYTLRYFTEVAYRNIDILDMSAEDFYSIISDDELNTR 252
            ..|:.:||..::...:.:.|.:|...|..:...::.||.........:|.       ::.:|..|
  Rat   235 PQLSLDNCYEVLSAGKRQRLSELRDAAYRFMCDHYLEVLREPAVFGRLSG-------AERDLLLR 292

  Fly   253 EEDHVWKLCVKWIDRNPESRKRHVAHL-MTGVRLGLMTPKCFMEEVKEHPYVLECEAAKPLIVDT 316
            ......:.|:.            .|.| .||.|.|                              
  Rat   293 RRLGTGRACLL------------AAALGTTGERSG------------------------------ 315

  Fly   317 FKFMYDLDFLNPQADELTTPPLAMPRLPHEVIFAIGGWSGGTSKGCIETYDTRADRWVTINAEDP 381
                                  :.|:.|       .|.:.......:..|...|..|..:.....
  Rat   316 ----------------------SRPQSP-------SGDAESRGDAAVYCYQAEAGEWRELTRLPE 351

  Fly   382 AGPRAYHGTAVLGFKIFSIGGY-----DG-VEYFNTCRVFDAVKKKWNEIAPMHCRRCYVSVTEL 440
            ..|....|..||...:|..||.     || ....:....::.|...|:.:.|:...|..|.:..|
  Rat   352 GAPARGCGLCVLFNYLFVAGGVAPAGPDGRARPSDQVFCYNPVTDCWSTVRPLRQARSQVQLLAL 416

  Fly   441 NGMIYAIGGYDGHNRLNTVERYNPRTNQWSVIPPMNMQRSDAS--ACTLQERIYATGGFNGQECL 503
            :|.:||:||    ..|.:||||:||.::|:.:.|:.......:  |.|....||.:||       
  Rat   417 DGHLYALGG----ECLLSVERYDPRADRWTAVAPLPRGAFAVAHEAATCNGEIYVSGG------- 470

  Fly   504 DSAEY----YDPVTNVWTRIPNMNHRRSGVSCVAFRNQLY--VIGGFNGTARLSTG 553
             |..|    |||..:.|...|..:.|......||....||  .:.|..|.|:.:||
  Rat   471 -SLFYRLLKYDPRRDEWQECPCSSSRERSADMVALDGFLYRFDLCGSRGDAQAATG 525

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klhl10NP_001015100.2 BTB 72..186 CDD:279045 24/124 (19%)
PHA03098 86..610 CDD:222983 95/484 (20%)
BACK 195..298 CDD:285009 16/103 (16%)
Kelch 347..394 CDD:128874 7/46 (15%)
KELCH repeat 385..428 CDD:276965 10/48 (21%)
Kelch 396..442 CDD:128874 11/51 (22%)
Kelch_1 431..476 CDD:279660 17/44 (39%)
KELCH repeat 432..475 CDD:276965 16/42 (38%)
KELCH repeat 479..523 CDD:276965 13/49 (27%)
Kelch 490..536 CDD:128874 14/49 (29%)
Kelch_1 525..570 CDD:279660 10/31 (32%)
KELCH repeat 526..571 CDD:276965 9/30 (30%)
Kelch_1 573..617 CDD:279660
KELCH repeat 573..617 CDD:276965
Kbtbd11NP_001100796.1 BTB 147..237 CDD:197585 20/107 (19%)
BTB 147..233 CDD:279045 20/103 (19%)
BACK_like 237..>276 CDD:297737 8/38 (21%)
Kelch_1 354..405 CDD:279660 12/50 (24%)
KELCH repeat 356..404 CDD:276965 10/47 (21%)
KELCH repeat 408..448 CDD:276965 17/43 (40%)
Kelch 419..455 CDD:128874 13/39 (33%)
Kelch_1 456..490 CDD:279660 12/41 (29%)
KELCH repeat 496..546 CDD:276965 9/30 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1072
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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