DRSC/TRiP Functional Genomics Resources

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Protein Alignment klhl10 and Klhdc8b

DIOPT Version :9

Sequence 1:NP_001015100.2 Gene:klhl10 / 3354863 FlyBaseID:FBgn0040038 Length:767 Species:Drosophila melanogaster
Sequence 2:NP_001007686.1 Gene:Klhdc8b / 306589 RGDID:1359445 Length:354 Species:Rattus norvegicus


Alignment Length:312 Identity:80/312 - (25%)
Similarity:127/312 - (40%) Gaps:24/312 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly   336 PPLAMPRLPHEV------IFAIGGWS-GGTSKGCIETYDTRADRWVTINAEDPAGPRAYHGTAVL 393
            ||:...|:...|      :..:||.. .|......||.|..:..|:.: |..|.. ||.....||
  Rat    15 PPMPTCRVYGTVAHQDGHLLVLGGCGRAGLPLDTAETLDMASHTWLAL-APLPTA-RAGAAAVVL 77

  Fly   394 GFKIFSIGGYDGVEY-FNTCRVFDAVKKKWNEIAPMHCRRCYVSVTELNGMIYAIGGYDGHNRLN 457
            |.::..:||.|.|:. ......|.|.:.:|...|.:......|:..|.:||:||:||........
  Rat    78 GKQVLVVGGVDEVQSPVAAVEAFLADEGRWERRATLPQAAMGVATVERDGMVYALGGMGPDTAPQ 142

  Fly   458 T-VERYNPRTNQWSVIPPMNMQRSDASACTLQERIYATGGFNGQECLDSAEYYDPVTNVWTRIPN 521
            . |..|..|.::|..:|.|......||......:||..||..|:..:.:.|.:|..|..|||.|:
  Rat   143 AQVLVYESRRDRWLSLPSMPTPCYGASTFLHGNKIYVLGGRQGKLPVTAFEAFDLETRTWTRHPS 207

  Fly   522 MNHRRSGVSCVAFRNQLYVIGGF------NGTAR---LSTGERFDPDTQTWHFI---REMNHSRS 574
            :..||:...|......::.:||.      |..:|   ::|.|.||.:..:|..:   ..|...|:
  Rat   208 LPSRRAFAGCAMAEGSVFSLGGLQQPGPHNFYSRPHFVNTVEMFDLEHGSWTKLPRSLRMRDKRA 272

  Fly   575 NFGLEIIDDMIFAIGGF-NGVSTISHTECYVAETDEWMEATDMNIVRSALSA 625
            :|.:..:...|.||||. |....::..|.:......|.....|...|.:.|:
  Rat   273 DFVVGSLGGNIVAIGGLGNQPCPLASVESFSLARRRWEALPAMPTARCSCSS 324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
klhl10NP_001015100.2 BTB 72..186 CDD:279045
PHA03098 86..610 CDD:222983 76/295 (26%)
BACK 195..298 CDD:285009
Kelch 347..394 CDD:128874 13/53 (25%)
KELCH repeat 385..428 CDD:276965 13/43 (30%)
Kelch 396..442 CDD:128874 10/46 (22%)
Kelch_1 431..476 CDD:279660 13/45 (29%)
KELCH repeat 432..475 CDD:276965 13/43 (30%)
KELCH repeat 479..523 CDD:276965 14/43 (33%)
Kelch 490..536 CDD:128874 15/45 (33%)
Kelch_1 525..570 CDD:279660 12/56 (21%)
KELCH repeat 526..571 CDD:276965 12/56 (21%)
Kelch_1 573..617 CDD:279660 10/44 (23%)
KELCH repeat 573..617 CDD:276965 10/44 (23%)
Klhdc8bNP_001007686.1 Kelch 1 1..31 4/15 (27%)
PHA03098 <9..210 CDD:222983 54/196 (28%)
KELCH repeat 21..66 CDD:276965 10/45 (22%)
Kelch 2 32..79 13/48 (27%)
KELCH repeat 69..113 CDD:276965 13/43 (30%)
Kelch 3 81..127 10/45 (22%)
KELCH repeat 117..162 CDD:276965 13/44 (30%)
Kelch 4 128..175 13/46 (28%)
PHA03098 <129..336 CDD:222983 50/196 (26%)
KELCH repeat 165..210 CDD:276965 14/44 (32%)
Kelch 5 176..222 15/45 (33%)
KELCH repeat 212..262 CDD:276965 11/49 (22%)
Kelch 6 224..281 12/56 (21%)
KELCH repeat 271..317 CDD:276965 11/45 (24%)
Kelch 7 282..329 11/43 (26%)
Kelch 8 331..354
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1072
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X9
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.900

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