Protein Alignment klhl10 and LOC1281663

DIOPT Version :10

• Sequence 1: NP_001015100.2
• Gene: klhl10 / 3354863
• FlyBaseID: FBgn0040038
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: XP_061497908.1
• Gene: LOC1281663 / 1281663
• VectorBaseID: AGAMI1_004119
• Length: 675
• Species: Anopheles gambiae
• Alignment Length: 584
• Identity: 181/584 - (30%)
• Similarity: 273/584 - (46%)
• Gaps: 44/584 - (7%)

  Fly    65 SDEALNTLNELREQNLLCDAQISVGEDVFNV--HRAIMCSCSSYFRAQFTGFNADTPGCVDGSDA 127
            ||..|..:.:..:...|||..:..|.|...:  ||.::.:.|:||.|.||           |...
Mosquito    49 SDVVLKRMQDYLQSEKLCDVVLIAGVDGRRIPAHRLVLSASSAYFSAMFT-----------GQLR 102

  Fly   128 KKNNNFIHIPGVSSCIMNCVIQYAYLRQTNISESNVHELLICADYVGMVGLVKKCKDYLGRILTP 192
            :.....|.:..||...:|.:|||.|.....|.|..|..||..|..:.:..:|..|.::|.|.|.|
Mosquito   103 ESQQEEITLQEVSGDALNSLIQYCYTGAIEIREDTVETLLATACLLQLSTIVGACCNFLARQLHP 167

  Fly   193 ENCVSIMGFARFRFLEDLHLKARNYTLRYFTEVAYRNIDILDMSAEDFYSIISDDELNTREEDHV 257
            .||:....||..:....|...|..||.::|.:| ::|.:...:.|....:::..|:||...|..|
Mosquito   168 SNCLGFSLFAEQQGCTALLKLATAYTCQHFQQV-WKNQEFFMLDAAQLANLLRSDDLNVPNEQEV 231

  Fly   258 WKLCVKWIDRNPESRKRHVAHLMTGVRLGLMTPKCFMEEVKEHPYVL-----ECEAAKPLIVDTF 317
            :...:.||..:.|.||||:..|:..::|.|:.|...::.|:    .|     ||:   .|:::.|
Mosquito   232 FHALMAWIQYDAEGRKRHIPELLALIKLPLLQPSFIVDHVE----ALCGGANECQ---QLVMEAF 289

  Fly   318 KFMYDLDFLNPQADELTTPPLAMPR-LPHEVIFAIGGWSGGTSKGCIETYDTRADRWVTINAEDP 381
            |:     .|.|....|.:.....|| .....:.|:||..|......||:||.|.|:|..:  ::.
Mosquito   290 KW-----HLIPGRRSLISTSRTRPRKSTMGRLLAVGGMDGHKGAISIESYDPRLDKWTLL--KNM 347

  Fly   382 AGPRAYHGTAVLGFKIFSIGGYDGVEYFNTCRVFDAVKKKWNE-IAPMHCRRCYVSVTELNGMIY 445
            ...|...|.|||..|:..:||.||::..||...||.....|:. :.||...|..:.|..|.|.:|
Mosquito   348 PTRRLQFGVAVLDDKLIIVGGRDGLKTLNTVDSFDLNTMCWSTLVPPMGTPRHGLGVAFLEGPLY 412

  Fly   446 AIGGYDGHNRLNTVERYNPRTNQWSVIPPMNMQRSDASACTLQERIYATGGFNGQECLDSAEYYD 510
            |:||:||.:.||||||::|....||.:.||:..||.|....|..|:|..||.:|..|..:.|.||
Mosquito   413 AVGGHDGWSYLNTVERWDPSARTWSYVAPMSAMRSTAGVAVLGGRLYVIGGRDGSVCHRTVECYD 477

  Fly   511 PVTNVWTRIPNMNHRRSGVSCVAFRNQLYVIGGFN------GTARLSTGERFDPDTQTWHFIREM 569
            |.||.||....||.||..|........||.:||.:      ...|..|.||:||.|.||..|..:
Mosquito   478 PHTNKWTLRAPMNQRRGCVGVGVLNGFLYALGGHDCPPSNPAVCRTDTVERYDPTTDTWTLIASL 542

  Fly   570 NHSRSNFGLEIIDDMIFAIGGFNGVSTISHTECYVAETDEWMEATDMNIVRSALSANNIAGLPN 633
            :..|...|:.::.|.:.|:||::|:..:...|.|.|||:||.....:|..|:...   :..:||
Mosquito   543 SVGRDAIGVSVLGDWLVALGGYDGIQYLKIVEQYDAETNEWTPIAPVNYSRAGAC---VVAIPN 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB_POZ	62..>108	CDD:453885	12/44 (27%)
		PHA03098	86..610	CDD:222983	169/538 (31%)
		KELCH repeat	385..428	CDD:276965	15/43 (35%)
		KELCH repeat	432..475	CDD:276965	19/42 (45%)
		KELCH repeat	479..523	CDD:276965	18/43 (42%)
		KELCH repeat	526..571	CDD:276965	16/50 (32%)
		KELCH repeat	573..617	CDD:276965	14/43 (33%)
LOC1281663	XP_061497908.1	None