Protein Alignment klhl10 and kbtbd3

DIOPT Version :10

• Sequence 1: NP_001015100.2
• Gene: klhl10 / 3354863
• FlyBaseID: FBgn0040038
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: XP_002934972.1
• Gene: kbtbd3 / 100490420
• XenbaseID: XB-GENE-6044137
• Length: 607
• Species: Xenopus tropicalis
• Alignment Length: 597
• Identity: 143/597 - (23%)
• Similarity: 232/597 - (38%)
• Gaps: 83/597 - (13%)

  Fly    63 IVSD----EALNTLNELREQNLLCDAQISVGEDVFNVHRAIMCSCSSYFRAQFTGFNADTPGCVD 123
            |||:    :.|:.|...|:|....|..|.|.:.:...||.::.:.|.:|||.|           :
 Frog    25 IVSECHGQQILSILQNFRDQKAFFDFNIIVKDQLMPCHRCVLAASSDFFRAMF-----------E 78

  Fly   124 GSDAKKNNNFIHIPGVSSCIMNCVIQYAYLRQTNISESNVHELLICADYVGMVGLVKKCKDYLGR 188
            .:..:::...:.|..:||..:...:.|||..:..|::.||..|...:.::.:..|.|.|.|:|.:
 Frog    79 VNMKERDGGSVTISNLSSNAVAAFLDYAYTGKAEITDENVDMLFQMSSFLQVPLLSKACSDFLIK 143

  Fly   189 ILTPENCVSIMGFARFRFLEDLHLKARNYTLRYFTEVAYRNIDILDMSAEDFYSIISDDELNTRE 253
            |:...||:.::..:.......|...|..::|::|: :..::.|.|:::.......:.||.||..|
 Frog   144 IIDTNNCLQLLSISESYGSTRLFDHALEFSLQHFS-LLTQSTDFLELNIGVLEKCLEDDLLNVPE 207

  Fly   254 EDHVWKLCVKWIDRNPESRKRHVAHLMTGVRLGLMTPKCFMEEVKEHPYVLECEAAKPLIVDTFK 318
            |:......:.|...:.:.|:|....|:..:||..::.......:.....:|:.......|....|
 Frog   208 EESALVAVIAWTKHSLDKRERFFPRLLRTIRLHQLSQSTLQNVLISEDQLLKSTDCLSTINSAIK 272

  Fly   319 FMYDLDFLNPQADELTTPPLAMPRLPHEVIFAIGGWSGGTSKGCIETYDTRADRWVT---INAED 380
            .:.....|.|.|...||..........|        .|||.  |...|:.:.|:|:.   |...|
 Frog   273 RVEAAGGLFPDARLSTTEKYIFVHKTAE--------DGGTQ--CTFCYNLKTDKWLELPHIQLTD 327

  Fly   381 PAGPRAYHGTAVLGFKIFSIGGYDGVEYFNTCR---------VFDAVKKKW--------NEIAP- 427
            ..|    ...:..|.|||..||..|    :.||         ..||..:.|        :.:.|
 Frog   328 LPG----SSLSSYGEKIFITGGCKG----HCCRGVRLHIAEPYHDATDQTWCYCPASNNSSLVPA 384

  Fly   428 -MHCRRCYVSVTELNGMIYAIGG--YDGH--NRLNTVERYNPRTNQW-SVIP-PMNMQRSDASAC 485
             ...|..:.||..|| .::.|||  ...|  ..|..||.|||...:| ||.| |..:...:||||
 Frog   385 MKKPRTMHTSVMALN-QLFVIGGKTKGAHYIKSLLDVESYNPLAKEWKSVSPLPRGIYYPEASAC 448

  Fly   486 -----TLQERIYATGGFNGQECLDSAEYYDPVTNVWTRIP---NMNHRRSGVSCVAFRNQLYVIG 542
                 .|...:..|..||  ..||....|:..||.|..:.   ......:.:..|...|.||:
 Frog   449 KNVIYVLGSEVEITDAFN--PSLDCFFKYNAETNQWCELVAEFGQFFHATLIKAVPVNNTLYI-- 509

  Fly   543 GFNGTARLSTGE--RFDPDTQTWHFIREMNHSRSNFGLEIIDDMIFAIGGFNGVSTIS-HTECYV 604
                 ..|||.:  .|.|:|..|........:..|.|...|:|.|:.:||......|: ..:.|.
 Frog   510 -----CDLSTYKVYSFCPETCVWKGEGSFECAGFNAGAVGIEDKIYILGGDYAPDEITDEVQVYH 569

  Fly   605 AETDEWMEATDM 616
            :...||.|.:.|
 Frog   570 SNRSEWEEVSPM 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB_POZ	62..>108	CDD:453885	13/48 (27%)
		PHA03098	86..610	CDD:222983	131/562 (23%)
		KELCH repeat	385..428	CDD:276965	13/61 (21%)
		KELCH repeat	432..475	CDD:276965	18/48 (38%)
		KELCH repeat	479..523	CDD:276965	14/51 (27%)
		KELCH repeat	526..571	CDD:276965	11/46 (24%)
		KELCH repeat	573..617	CDD:276965	13/45 (29%)
kbtbd3	XP_002934972.1	BTB_POZ_KBTBD3_BKLHD3	24..153	CDD:349580	35/138 (25%)
		PHA03098	62..582	CDD:222983	133/560 (24%)
		KELCH repeat	330..385	CDD:276965	14/62 (23%)
		KELCH repeat	389..437	CDD:276965	19/48 (40%)
		KELCH repeat	440..485	CDD:276965	14/46 (30%)
		KELCH repeat	537..582	CDD:276965	13/45 (29%)