Protein Alignment klhl10 and klhl10a

DIOPT Version :9

• Sequence 1: NP_001015100.2
• Gene: klhl10 / 3354863
• FlyBaseID: FBgn0040038
• Length: 767
• Species: Drosophila melanogaster
• Sequence 2: XP_017207208.1
• Gene: klhl10a / 100333629
• ZFINID: ZDB-GENE-131015-1
• Length: 552
• Species: Danio rerio
• Alignment Length: 567
• Identity: 243/567 - (42%)
• Similarity: 349/567 - (61%)
• Gaps: 31/567 - (5%)

  Fly    86 ISVGEDVFNV-HRAIMCSCSSYFRAQFTGFNADTPGCVDGSDAKKNNNFIHIPGVSSCIMNCVIQ 149
            |.:.:...|| ||.:       |..|:|             ..|::.||   |.:||..|:.:||
Zfish     5 IFIKQHCLNVLHRML-------FSTQWT-------------KPKQHFNF---PEMSSDTMSLIIQ 46

  Fly   150 YAYLRQTNISESNVHELLICADYVGMVGLVKKCKDYLGRILTPENCVSIMGFA-RFRFLEDLHLK 213
            :||.|...|:|.||.|||:.||.:.:.||.:.|..:|....:.:||:.|..|. ||....:||.|
Zfish    47 HAYARPVQITEDNVCELLVAADQLLISGLTEACCKFLEANFSLQNCIGIWAFTERFHSCTELHHK 111

  Fly   214 ARNYTLRYFTEVAYRNIDILDMSAEDFYSIISDDELNTREEDHVWKLCVKWIDRNPESRKRHVAH 278
            |..|.|::|.||...:.:.|.:..|...::||.||||.::|:.|::..::||:..||:|:.|:..
Zfish   112 AEFYVLQHFQEVQQVSEEFLQLPLELLENMISRDELNVKQEEVVFEAILRWINHEPENRRNHITA 176

  Fly   279 LMTGVRLGLMTPKCFMEEVKEHPYVLECEAAKPLIVDTFKFMYDLDFLNPQADELTTPPLAMPRL 343
            |::.||||||:|:.||..|:.:|.|||.||...:|::..|.::|| .:.|.:..|.: .:...|:
Zfish   177 LLSRVRLGLMSPEYFMNNVRNNPLVLENEACSFIIINAMKVIFDL-HVEPTSSGLVS-YMTRQRM 239

  Fly   344 PHEVIFAIGGWSGGTSKGCIETYDTRADRWVTINAEDPAGPRAYHGTAVLGFKIFSIGGYDGVEY 408
            |.||:.||||||.|.....||.|||||:.|..:..|:.. ||||||.|||...|:::||:|...|
Zfish   240 PSEVLLAIGGWSIGNPTNGIEAYDTRANCWKDVTVENEL-PRAYHGVAVLDGFIYAVGGFDSENY 303

  Fly   409 FNTCRVFDAVKKKWNEIAPMHCRRCYVSVTELNGMIYAIGGYDGHNRLNTVERYNPRTNQWSVIP 473
            |::.|.|:.|...|:|:|||:.|||||||..|:|::|||||::||.||.|.|.||..||||:.|.
Zfish   304 FSSVRKFNPVTHTWHEVAPMYERRCYVSVAVLDGLLYAIGGFNGHARLKTAECYNKNTNQWTQIS 368

  Fly   474 PMNMQRSDASACTLQERIYATGGFNGQECLDSAEYYDPVTNVWTRIPNMNHRRSGVSCVAFRNQL 538
            ||:.:||||||.:|..::|..|||.|.|||.:||.::|.||.|:.|..|..|||||..:.|.|.:
Zfish   369 PMSERRSDASATSLHGKVYICGGFTGVECLFTAESFNPETNQWSLIEPMRTRRSGVGVITFGNLI 433

  Fly   539 YVIGGFNGTARLSTGERFDPDTQTWHFIREMNHSRSNFGLEIIDDMIFAIGGFNGVSTISHTECY 603
            |.:|||:|::||.:.|.:||.|.:||.|..|.::|||||:|:::|.:..:|||||..|.|..|.|
Zfish   434 YAVGGFDGSSRLRSVEAYDPHTDSWHDIESMINTRSNFGIEVVNDQLIVVGGFNGFRTCSDVEIY 498

  Fly   604 VAETDEWMEATDMNIVRSALSANNIAGLPNKRDYIHKERDRL--MEE 648
            ...|:||:|..||||.|||||...|:|||....|:. :||.|  :||
Zfish   499 NQSTNEWVEVCDMNISRSALSCCVISGLPQCLQYVF-DRDSLPMLEE 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
klhl10	NP_001015100.2	BTB	72..186	CDD:279045	32/100 (32%)
		PHA03098	86..610	CDD:222983	221/525 (42%)
		BACK	195..298	CDD:285009	40/103 (39%)
		Kelch	347..394	CDD:128874	25/46 (54%)
		KELCH repeat	385..428	CDD:276965	20/42 (48%)
		Kelch	396..442	CDD:128874	22/45 (49%)
		Kelch_1	431..476	CDD:279660	28/44 (64%)
		KELCH repeat	432..475	CDD:276965	26/42 (62%)
		KELCH repeat	479..523	CDD:276965	22/43 (51%)
		Kelch	490..536	CDD:128874	22/45 (49%)
		Kelch_1	525..570	CDD:279660	21/44 (48%)
		KELCH repeat	526..571	CDD:276965	21/44 (48%)
		Kelch_1	573..617	CDD:279660	21/43 (49%)
		KELCH repeat	573..617	CDD:276965	21/43 (49%)
klhl10a	XP_017207208.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170589420
Domainoid	1	1.000	72	1.000	Domainoid score	I9273
eggNOG	1	0.900	-	-		E1_KOG4441
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H12018
Inparanoid	1	1.050	483	1.000	Inparanoid score	I1406
OMA	1	1.010	-	-		QHG45628
OrthoDB	1	1.010	-	-		D145100at33208
OrthoFinder	1	1.000	-	-		FOG0005514
OrthoInspector	1	1.000	-	-		otm25990
orthoMCL	1	0.900	-	-		OOG6_105990
Panther	1	1.100	-	-	O	PTHR24412
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X9
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.770