Protein Alignment MFS17 and THI73

DIOPT Version :10

• Sequence 1: NP_001015096.2
• Gene: MFS17 / 3354861
• FlyBaseID: FBgn0058263
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_013104.1
• Gene: THI73 / 850690
• SGDID: S000003994
• Length: 523
• Species: Saccharomyces cerevisiae
• Alignment Length: 504
• Identity: 96/504 - (19%)
• Similarity: 181/504 - (35%)
• Gaps: 129/504 - (25%)

  Fly     7 SYSSPQDDVLTGRDGRETQSSLLRDKIPARLVLYFLSW--SGFLVSFMMRNDMNFALVAMIANDN 69
            |.::.:|||:.|.:.....|..|..|:..::.|:.|.:  ..:|:.|:.:..:|:| .:|...|:
Yeast    48 SSTANEDDVVAGEEANFYGSHELSPKVLRKVDLFILPFLCCTYLLMFLDKALLNYA-ASMGIKDH 111

  Fly    70 STQNQSLIKSQQILGTGT-DDQKTIVKSVVISSFYWCYVLSQVVGGVATELFGTKCVFGWSQLAT 133
                   :|..:....|| .....|....|::.....:.:|:::|...|       |:|......
Yeast   112 -------LKGNEFSNLGTIFSAAYIFMEPVVTYLIQKFPISKILGTFIT-------VWGIVLACH 162

  Fly   134 ALCSFMMPSAAQLHYIAVIVLRSIQGFASGLTWPAMYAIVGYWIPLTERSRFMSSFQGFSIGIGL 198
            |.|.         .|.:::|:|::.|.....:.....||.|.:        :..|.|...||...
Yeast   163 AACK---------TYASLMVVRTLLGLFESSSAVGCIAISGMY--------YTKSEQSARIGFWA 210

  Fly   199 TYPLCGFI---LSEWG-----------WPYIFYTTGTLGLGWCILWYLLAFNTPREHPRITKDE- 248
            |....|:|   |..:|           |..:|...|.:.:.:.:|.:|...:.......:.|:|
Yeast   211 TQAGTGYIVGGLISFGFLHYHGTAFTSWQIMFLVVGLVTVAFGVLTFLYLPDNVTNAWFLNKEEK 275

  Fly   249 --------LNYIELNVKKEVNSSVKV-----KVPWLQIF---------KSIPAWAIAIT-TFGRI 290
                    .|...|..||.....||.     |..|..:.         .:|..:::.|| |||
Yeast   276 IQVVEHIRANQTGLETKKFKKQQVKELFLHDKFTWPMLLLTACSQISTGAIGTFSVTITGTFG-- 338

  Fly   291 FVHY---------------IFIVNGPTFMGNVLKFNFETNGFLS---GVPFICS--YISSVLFCY 335
            |..|               |.::               |...||   .:..|.:  ||.:::.|.
Yeast   339 FDKYETALLQLPIGAITAMIILI---------------TTQMLSRWGHITLITTSMYIPAIIGCI 388

  Fly   336 IADKI-VFYKVLCLTNVRKVFTALSQIIPGVLIY--C--IGYIDNVY---ILLTVWFIAVIFITA 392
            :...: :.:|:..|.::..:::. |.:|..:.|:  |  .||...|:   |.:.|:.::.|....
Yeast   389 VLISLPLSHKIGNLFSLYLLYSG-SCVITNIYIWNSCNTSGYTKRVFRNAITMIVYNVSCIIAPQ 452

  Fly   393 SYAGAMANIIDLAPNYGHSAAVLAFCQTIHMSASFISPLTAGFIVTQED 441
            .:....      ||.|..:...|...|.:.:...    |..|:|..:|:
Yeast   453 MFRAYS------APRYIPAKIALLVTQCVCVPLQ----LYIGYICKKEN 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS17	NP_001015096.2	MFS_SLC17	40..468	CDD:340876	87/471 (18%)
THI73	NP_013104.1	MFS_FEN2_like	77..481	CDD:340885	84/463 (18%)