Protein Alignment MFS17 and SLC17A1

DIOPT Version :10

• Sequence 1: NP_001015096.2
• Gene: MFS17 / 3354861
• FlyBaseID: FBgn0058263
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_005065.2
• Gene: SLC17A1 / 6568
• HGNCID: 10929
• Length: 467
• Species: Homo sapiens
• Alignment Length: 474
• Identity: 134/474 - (28%)
• Similarity: 236/474 - (49%)
• Gaps: 45/474 - (9%)

  Fly    31 DKIPARLVLYFLSWSGFLVSFMM----------RNDMNFALVAMIANDNSTQNQSLIKSQQILGT 85
            :::|.:.|..|.|:. :.:||::          |..:|..:|.|:   |||....|        .
Human     5 NRLPPKKVPGFCSFR-YGLSFLVHCCNVIITAQRACLNLTMVVMV---NSTDPHGL--------P 57

  Fly    86 GTDDQKTI-------------VKSVVISSFYWCYVLSQVVGGVATELFGTKCVFGWSQLATALCS 137
            .|..:|.:             ::.:::||..:..::.||..|..:.::.||.:.|::...:::.|
Human    58 NTSTKKLLDNIKNPMYNWSPDIQGIILSSTSYGVIIIQVPVGYFSGIYSTKKMIGFALCLSSVLS 122

  Fly   138 FMMPSAAQLHYIAVIVLRSIQGFASGLTWPAMYAIVGYWIPLTERSRFMS-SFQGFSIGIGLTYP 201
            .::|.||.:....|:|.|::||.|.|:...|.:.|...|.|..||.|..| |..||.:|..:...
Human   123 LLIPPAAGIGVAWVVVCRAVQGAAQGIVATAQFEIYVKWAPPLERGRLTSMSTSGFLLGPFIVLL 187

  Fly   202 LCGFILSEWGWPYIFYTTGTLGLGWCILWYLLAFNTPREHPRITKDELNYIELNVKKEVNSSVKV 266
            :.|.|....|||.:||..|..|...|:||::|.::.|::||.|:..|..||..::.::|:|| :.
Human   188 VTGVICESLGWPMVFYIFGACGCAVCLLWFVLFYDDPKDHPCISISEKEYITSSLVQQVSSS-RQ 251

  Fly   267 KVPWLQIFKSIPAWAIAITTFGRIFVHYIFIVNGPTFMGNVLKFNFETNGFLSGVPFICSYISSV 331
            .:|...|.||:|.|||:..:|...:.|.|..:..|.|:.::|..|.:.|||||.:|::.::|...
Human   252 SLPIKAILKSLPVWAISTGSFTFFWSHNIMTLYTPMFINSMLHVNIKENGFLSSLPYLFAWICGN 316

  Fly   332 LFCYIADKIVFYKVLCLTNVRKVFTALSQIIPGVLIYCIGYIDNVYILLTVWFIAVIFITASY-- 394
            |...::|..:...:|.:..|||:|||...::|.:...|:.|:.:.:..:.: |:.:...|.|:
Human   317 LAGQLSDFFLTRNILSVIAVRKLFTAAGFLLPAIFGVCLPYLSSTFYSIVI-FLILAGATGSFCL 380

  Fly   395 AGAMANIIDLAPNYGHSAAVLAFCQTI-HMSASFISPLTAGFIVTQEDSIDQWRRVFEVSAIISI 458
            .|...|.:|:||.|   ...:..|.|: .|....|:....|.|:.| |....|.:.|.:.|.|::
Human   381 GGVFINGLDIAPRY---FGFIKACSTLTGMIGGLIASTLTGLILKQ-DPESAWFKTFILMAAINV 441

  Fly   459 LTYLFYQLFGTAEIQTWNK 477
            ...:||.:..|||||.|.|
Human   442 TGLIFYLIVATAEIQDWAK 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS17	NP_001015096.2	MFS_SLC17	40..468	CDD:340876	125/454 (28%)
SLC17A1	NP_005065.2	2A0114euk	3..466	CDD:129972	134/474 (28%)