Protein Alignment MFS17 and SLC17A6

DIOPT Version :10

• Sequence 1: NP_001015096.2
• Gene: MFS17 / 3354861
• FlyBaseID: FBgn0058263
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_065079.1
• Gene: SLC17A6 / 57084
• HGNCID: 16703
• Length: 582
• Species: Homo sapiens
• Alignment Length: 477
• Identity: 138/477 - (28%)
• Similarity: 242/477 - (50%)
• Gaps: 16/477 - (3%)

  Fly    33 IPARLVLYFLSWSGFLVSFMMRNDMNFALVAMIANDNSTQNQSLIKSQQILGTGTDDQKTIVKSV 97
            :|.|.::..:|..||.:||.:|.::..|:|.|:.|....:...:||.:.....   |.:|:  .:
Human    67 LPRRYIIAIMSGLGFCISFGIRCNLGVAIVDMVNNSTIHRGGKVIKEKAKFNW---DPETV--GM 126

  Fly    98 VISSFYWCYVLSQVVGGVATELFGTKCVFGWSQLATALCSFMMPSAAQLHYIAVIVLRSIQGFAS 162
            :..||:|.|:::|:.||..........|||.:.|.|:..:.::||||::||..||.:|.:||...
Human   127 IHGSFFWGYIITQIPGGYIASRLAANRVFGAAILLTSTLNMLIPSAARVHYGCVIFVRILQGLVE 191

  Fly   163 GLTWPAMYAIVGYWIPLTERSRF-MSSFQGFSIGIGLTYPLCGFILSEWGWPYIFYTTGTLGLGW 226
            |:|:||.:.|...|.|..||||. .:||.|...|..:..||.|.::...||..:||..|:.|:.|
Human   192 GVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGSFGMVW 256

  Fly   227 CILWYLLAFNTPREHPRITKDELNYIELNVKKEVN---SSVKVKVPWLQIFKSIPAWAIAITTFG 288
            .:.|.|:::.:|.:||.||.:|..|||.::.:..|   :..|.|.||.:.|.|:|.:||.:..|.
Human   257 YMFWLLVSYESPAKHPTITDEERRYIEESIGESANLLGAMEKFKTPWRKFFTSMPVYAIIVANFC 321

  Fly   289 RIFVHYIFIVNGPTFMGNVLKFNFETNGFLSGVPFICSYISSVLFCYIADKIVFYKVLCLTNVRK 353
            |.:..|:.:::.|.:...|..|.....|.||.||.:...|...:...|||.:...::|..|.|||
Human   322 RSWTFYLLLISQPAYFEEVFGFEISKVGMLSAVPHLVMTIIVPIGGQIADFLRSKQILSTTTVRK 386

  Fly   354 VFTALSQIIPGVLIYCIGYIDNVYILLTVWFIAVIFITASYAGAMANIIDLAPNYGHSAAVLAFC 418
            :.......:...|:..:||.....:.::...:||.|...:.:|...|.:|:||.|  ::.::...
Human   387 IMNCGGFGMEATLLLVVGYSHTRGVAISFLVLAVGFSGFAISGFNVNHLDIAPRY--ASILMGIS 449

  Fly   419 QTIHMSASFISPLTAGFIVTQEDSIDQWRRVFEVSAIISILTYLFYQLFGTAEIQTWNKGLPVND 483
            ..:...:..:.|:..| .:|:..|.::|:.||.::|::.....:||.:|.:.|.|.|..    .:
Human   450 NGVGTLSGMVCPIIVG-AMTKNKSREEWQYVFLIAALVHYGGVIFYAIFASGEKQPWAD----PE 509

  Fly   484 DSDEGKVLSTAKDDLDNTGGPI 505
            ::.|.|.....:|:||...|.|
Human   510 ETSEEKCGFIHEDELDEETGDI 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS17	NP_001015096.2	MFS_SLC17	40..468	CDD:340876	125/431 (29%)
SLC17A6	NP_065079.1	MFS_SLC17A6_7_8_VGluT	74..498	CDD:340940	125/431 (29%)