Protein Alignment MFS17 and eat-4

DIOPT Version :10

• Sequence 1: NP_001015096.2
• Gene: MFS17 / 3354861
• FlyBaseID: FBgn0058263
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_499023.3
• Gene: eat-4 / 176291
• WormBaseID: WBGene00001135
• Length: 576
• Species: Caenorhabditis elegans
• Alignment Length: 494
• Identity: 130/494 - (26%)
• Similarity: 219/494 - (44%)
• Gaps: 58/494 - (11%)

  Fly    32 KIPARLVLYFLSWSGFLVSFMMRNDMNFALVAMIANDNSTQNQSLIKSQQILGTGTDDQKTIVKS 96
            |...|.:|..|:..||::||.:|  .||.........|.|.....:...:.  ..|.|:    .|
 Worm    65 KCRKRWLLAILANMGFMISFGIR--CNFGAAKTHMYKNYTDPYGKVHMHEF--NWTIDE----LS 121

  Fly    97 VVISSFYWCYVLSQVVGGVATELFGTKCVFGWSQLATALCSFMMPSAAQL--HYIAVIVLRSIQG 159
            |:.||:::.|:::|:..|.....|....:||:.....|..:.::|...::  .|: |..::..||
 Worm   122 VMESSYFYGYLVTQIPAGFLAAKFPPNKLFGFGIGVGAFLNILLPYGFKVKSDYL-VAFIQITQG 185

  Fly   160 FASGLTWPAMYAIVGYWIPLTERSRF-MSSFQGFSIGIGLTYPLCGFILSEWGWPYIFYTTGTLG 223
            ...|:.:|||:.:..||.|..|||:. .::|.|...|..|..||..|::|...|...||..|..|
 Worm   186 LVQGVCYPAMHGVWRYWAPPMERSKLATTAFTGSYAGAVLGLPLSAFLVSYVSWAAPFYLYGVCG 250

  Fly   224 LGWCILWYLLAFNTPREHPRITKDELNYIELNVKKEVNSSVKVK-VPWLQIFKSIPAWAIAITTF 287
            :.|.|||:.:.|..|..||.|:::|..:||..:....|:...:: :||..|..|.|.|||.:..|
 Worm   251 VIWAILWFCVTFEKPAFHPTISQEEKIFIEDAIGHVSNTHPTIRSIPWKAIVTSKPVWAIIVANF 315

  Fly   288 GRIFVHYIFIVNGPTFMGNVLKFNFETNGFLSGVPFICSYISSVLFCYI------ADKIVFYKVL 346
            .|.:..|:.:.|..|:|...|......:|.|:.:|.:      |:.|.:      ||.:...|:|
 Worm   316 ARSWTFYLLLQNQLTYMKEALGMKIADSGLLAAIPHL------VMGCVVLMGGQLADYLRSNKIL 374

  Fly   347 CLTNVRKVFTALSQIIPGVLIYCIGYIDNVYILLTVWF-----------IAVIFITA-SYAGAMA 399
            ..|.|||:|.            |.|:......:|.|.:           ||.:.::. :.:|...
 Worm   375 STTAVRKIFN------------CGGFGGEAAFMLIVAYTTSDTTAIMALIAAVGMSGFAISGFNV 427

  Fly   400 NIIDLAPNYGHSAAVLAFCQTIHMSASFISP-LTAGFIVTQEDSIDQWRRVFEVSAIISILTYLF 463
            |.:|:||.|  :|.::.|...|...|....| :|..|....:..   |..||.::::|......|
 Worm   428 NHLDIAPRY--AAILMGFSNGIGTLAGLTCPFVTEAFTAHSKHG---WTSVFLLASLIHFTGVTF 487

  Fly   464 YQLFGTAEIQTWNKGLPVNDDSDEGKVLSTAKDDLDNTG 502
            |.::.:.|:|.|.:  |..::....|.| ..|..::.||
 Worm   488 YAVYASGELQEWAE--PKEEEEWSNKEL-VNKTGINGTG 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS17	NP_001015096.2	MFS_SLC17	40..468	CDD:340876	118/450 (26%)
eat-4	NP_499023.3	MFS_SLC17A6_7_8_VGluT	73..492	CDD:340940	118/450 (26%)