Protein Alignment MFS17 and SLC17A3

DIOPT Version :10

• Sequence 1: NP_001015096.2
• Gene: MFS17 / 3354861
• FlyBaseID: FBgn0058263
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_001091956.1
• Gene: SLC17A3 / 10786
• HGNCID: 10931
• Length: 498
• Species: Homo sapiens
• Alignment Length: 494
• Identity: 139/494 - (28%)
• Similarity: 242/494 - (48%)
• Gaps: 45/494 - (9%)

  Fly    17 TGRDGRETQ-----SSLLRDKIPA--------RLVLYFLSWSGFLVSFMMRNDMNFALVAMIAND 68
            |.|:.:..|     .:|:..|:|:        .|||:|.:::....:.:    ||..:|||:
Human    10 TARESKNAQDMQVDETLIPRKVPSLCSARYGIALVLHFCNFTTIAQNVI----MNITMVAMV--- 67

  Fly    69 NSTQNQS-LIKSQQIL-----GTGTDDQKTI------------VKSVVISSFYWCYVLSQVVGGV 115
            |||..|| |..|.::|     |..:...|::            ::.::..:..:..:|:....|.
Human    68 NSTSPQSQLNDSSEVLPVDSFGGLSKAPKSLPAKAPVYDWSPQIQGIIFGAVGYGGILTMAPSGY 132

  Fly   116 ATELFGTKCVFGWSQLATALCSFMMPSAAQLHYIAVIVLRSIQGFASGLTWPAMYAIVGYWIPLT 180
            .....|||.|.|.|..||:..:..:|.|.....:.:||.|.:||.:........:||...|.|..
Human   133 LAGRVGTKRVVGISLFATSFLTLCIPLATDFGIVLLIVTRIVQGLSQSSILGGQFAIWEKWGPPQ 197

  Fly   181 ERSRFMS-SFQGFSIGIGLTYPLCGFILSEWGWPYIFYTTGTLGLGWCILWYLLAFNTPREHPRI 244
            ||||..| :..|..:|......:.|||....|||::||..|.:|...|:||:::.::.|..:|.|
Human   198 ERSRLCSIALSGMLLGCFTAILIGGFISETLGWPFVFYIFGGVGCVCCLLWFVVIYDDPVSYPWI 262

  Fly   245 TKDELNYIELNVKKEVNSSVKVKVPWLQIFKSIPAWAIAITTFGRIFVHYIFIVNGPTFMGNVLK 309
            :..|..||..::|::|.|| |..:|...:.:|:|.|:|.:..|...::....:|..||::.:|..
Human   263 STSEKEYIISSLKQQVGSS-KQPLPIKAMLRSLPIWSICLGCFSHQWLVSTMVVYIPTYISSVYH 326

  Fly   310 FNFETNGFLSGVPFICSYISSVLFCYIADKIVFYKVLCLTNVRKVFTALSQIIPGVLIYCIGYID 374
            .|...||.||.:|||.:::..::..|:||.::..|...:| |||:.|.|..:....||..:.|::
Human   327 VNIRDNGLLSALPFIVAWVIGMVGGYLADFLLTKKFRLIT-VRKIATILGSLPSSALIVSLPYLN 390

  Fly   375 NVYILLTVWF-IAVIFITASYAGAMANIIDLAPNYGHSAAVLAFCQTIHMSASFISPLTAGFIVT 438
            :.||..|... ::....|...:|...|::|:||.|  |:.::...:.....|..|.|..:||:::
Human   391 SGYITATALLTLSCGLSTLCQSGIYINVLDIAPRY--SSFLMGASRGFSSIAPVIVPTVSGFLLS 453

  Fly   439 QEDSIDQWRRVFEVSAIISILTYLFYQLFGTAEIQTWNK 477
            |:.... ||.||.:...:::|..|||.:||.|::|.|.|
Human   454 QDPEFG-WRNVFFLLFAVNLLGLLFYLIFGEADVQEWAK 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS17	NP_001015096.2	MFS_SLC17	40..468	CDD:340876	124/447 (28%)
SLC17A3	NP_001091956.1	MFS_SLC17	42..482	CDD:340876	127/451 (28%)