Protein Alignment MFS17 and SLC17A4

DIOPT Version :10

• Sequence 1: NP_001015096.2
• Gene: MFS17 / 3354861
• FlyBaseID: FBgn0058263
• Length: 505
• Species: Drosophila melanogaster
• Sequence 2: NP_005486.1
• Gene: SLC17A4 / 10050
• HGNCID: 10932
• Length: 497
• Species: Homo sapiens
• Alignment Length: 463
• Identity: 130/463 - (28%)
• Similarity: 234/463 - (50%)
• Gaps: 35/463 - (7%)

  Fly    37 LVLYFLSWSGFLVSFMMRNDMNFALVAMIANDNSTQNQSLIKSQQILGTGTDDQ----KTI---- 93
            |:|...::|    .:..:.:::.|:.||: |:.:..:|....:::   ..||.|    :|:
Human    41 LILQLCNFS----IYTQQMNLSIAIPAMV-NNTAPPSQPNASTER---PSTDSQGYWNETLKEFK 97

  Fly    94 -----------VKSVVISSFYWCYVLSQVVGGVATELFGTKCVFGWSQLATALCSFMMPSAAQLH 147
                       ::.:::||..:...|:.:..|....:||.|.|.|.....::..:..:|.||...
Human    98 AMAPAYDWSPEIQGIILSSLNYGSFLAPIPSGYVAGIFGAKYVVGAGLFISSFLTLFIPLAANAG 162

  Fly   148 YIAVIVLRSIQGFASGLTWPAMYAIVGYWIPLTERSRFMS-SFQGFSIGIGLTYPLCGFILSEWG 211
            ...:||||.:||.|..:.....|:|...|.|..|||:..: :..|..:|..:.....|.:....|
Human   163 VALLIVLRIVQGIAQVMVLTGQYSIWVKWAPPLERSQLTTIAGSGSMLGSFIVLLAGGLLCQTIG 227

  Fly   212 WPYIFYTTGTLGLGWCILWYLLAFNTPREHPRITKDELNYIELNVKKEVNSSVKVKVPWLQIFKS 276
            |||:||..|.:|...|.||:.|.::.|..||.|:..|..||..::.:: :.|....:|...:.||
Human   228 WPYVFYIFGGIGCACCPLWFPLIYDDPVNHPFISAGEKRYIVCSLAQQ-DCSPGWSLPIRAMIKS 291

  Fly   277 IPAWAIAITTFGRIFVHYIFIVNGPTFMGNVLKFNFETNGFLSGVPFICSYISSVLFCYIADKIV 341
            :|.|||.::.|...::.|..:...||::.:||:.|...:|.||.:||:...|..:|...:||.::
Human   292 LPLWAILVSYFCEYWLFYTIMAYTPTYISSVLQANLRDSGILSALPFVVGCICIILGGLLADFLL 356

  Fly   342 FYKVLCLTNVRKVFTALSQIIPGVLIYCIGYIDNVYILLTVWFIAVIFITASY--AGAMANIIDL 404
            ..|:|.|..:||:|||:..:.|.|::..:.::.:.: .:|:.|:.:....:|:  :||:.|.:|:
Human   357 SRKILRLITIRKLFTAIGVLFPSVILVSLPWVRSSH-SMTMTFLVLSSAISSFCESGALVNFLDI 420

  Fly   405 APNYGHSAAVLAFCQTIHMSASFISPLTAGFIVTQEDSIDQWRRVFEVSAIISILTYLFYQLFGT 469
            ||.|  :..:....|.....|..|||..|||.::| ||...||.||.:||.::|...:||.:||.
Human   421 APRY--TGFLKGLLQVFAHIAGAISPTAAGFFISQ-DSEFGWRNVFLLSAAVNISGLVFYLIFGR 482

  Fly   470 AEIQTWNK 477
            |::|.|.|
Human   483 ADVQDWAK 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MFS17	NP_001015096.2	MFS_SLC17	40..468	CDD:340876	122/449 (27%)
SLC17A4	NP_005486.1	MFS_SLC17	40..481	CDD:340876	124/452 (27%)