DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15408 and MAL31

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_009857.1	Gene:	MAL31 / 852601	SGDID:	S000000502	Length:	614	Species:	Saccharomyces cerevisiae

Alignment Length:	498	Identity:	101/498 - (20%)
Similarity:	192/498 - (38%)	Gaps:	100/498 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 TLLINVISISHG-----IGIGWLSPTLRK----LQSDSPAGFEVKSEFEISWVGSMLGM------ 73
            :||::...|..|     :|..:..|..:|    |.|::       .::||| |...:|:
Yeast   103 SLLVSTTLIQEGYDTAILGAFYALPVFQKKYGSLNSNT-------GDYEIS-VSWQIGLCLCYMA 159

  Fly    74 GSVTGNILIGCLLGRLGSKRCLLLIAIPHSCFWILVYFAQSVEYLYVGRLLAGICGGGMYIVHPI 138
            |.:.|..:.|..:..:|::..|::.....:.|..::||.:|:..:.||:.|.|:..|....:...
Yeast   160 GEIVGLQMTGPSVDYMGNRYTLIMALFFLAAFIFILYFCKSLGMIAVGQALCGMPWGCFQCLTVS 224

  Fly   139 LLSEIADANIR-------------GTFSAMVMLSVNVGILVGYIIGTHLPY-----YSIPLMVLI 185
            ..|||....:|             |...|..::..:........:|..||:     :.:||.|.|
Yeast   225 YASEICPLALRYYLTTYSNLCWAFGQLFAAGIMKNSQNKYANSELGYKLPFALQWIWPLPLAVGI 289

  Fly   186 LPLWYLISVLLFIKESPMHLIRIGKYSAAERSFRYYKNIKDSDNIHDQNRAMEEFEIMKIALTKG 250
                      .|..|||..|::.|:...|.||.....:.|..:.   :.....|.:.:|..:.|.
Yeast   290 ----------FFAPESPWWLVKKGRIDQARRSLERTLSGKGPEK---ELLVSMELDKIKTTIEKE 341

  Fly   251 DALQDAVTF----KDFYSRPALKAYGPALVLLIANQFSGLFTMVNYMSDIFANSG-STMDPDTCT 310
            ..:.|..|:    ||..:|...:    ...|....|.|...:::.|.:..:..:| ||....|.:
Yeast   342 QKMSDEGTYWDCVKDGINRRRTR----IACLCWIGQCSCGASLIGYSTYFYEKAGVSTDTAFTFS 402

  Fly   311 IIIGAVQILGTYVTTLLCDICGR----------KLLMLVSTGGVAISLTAFGFFTKYAESHNIGE 365
            ||...:.|..|:::......|||          :.:|....||:..|           ::|....
Yeast   403 IIQYCLGIAATFISWWASKYCGRFDLYAFGLAFQAIMFFIIGGLGCS-----------DTHGAKM 456

  Fly   366 YSWIPLLLMSMDIFLGNIGLVGCFFVSLVEMFPVKIRAK-------AASMAIVVCSIFVFLMLNI 423
            .|...|::::   |..|:|:....|..:.|:...::|.|       |.::..||.::.:...||
Yeast   457 GSGALLMVVA---FFYNLGIAPVVFCLVSEIPSSRLRTKTIILARNAYNVIQVVVTVLIMYQLN- 517

  Fly   424 FPICMKQWGISATMWSCAGVTALSSLYFTYF-MKETKGKSMLD 465
                .::|...|......|...|::|.:... :.||.|::.::
Yeast   518 ----SEKWNWGAKSGFFWGGFCLATLAWAVVDLPETAGRTFIE 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	89/440 (20%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	89/441 (20%)
MAL31	NP_009857.1	SP	74..557	CDD:273317	101/498 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342492
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830