DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15408 and HXT7

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_010629.3	Gene:	HXT7 / 851943	SGDID:	S000002750	Length:	570	Species:	Saccharomyces cerevisiae

Alignment Length:	490	Identity:	111/490 - (22%)
Similarity:	207/490 - (42%)	Gaps:	82/490 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 TLLINVISISH-GIGIGWLSPTLRKL--QSDSPAGFEVK--------SEFEISWVGSMLGMGSVT 77
            |:.|..|.|:. |...||.:.|:...  |:|....|.:|        |:.....:.|:..:|...
Yeast    64 TVSIMCIMIAFGGFVFGWDTGTISGFINQTDFIRRFGMKHKDGTNYLSKVRTGLIVSIFNIGCAI 128

  Fly    78 GNILIGCLLGRLGSKRCLLLIAIPHSCFWILVYFAQSVEY--LYVGRLLAGICGGGMYIVHPILL 140
            |.|::..|....|.|..|:::.:.: ...|::..|...::  .::||:::|:..||:.::.|:|:
Yeast   129 GGIILSKLGDMYGRKVGLIVVVVIY-IIGIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLI 192

  Fly   141 SEIADANIRGTFSAMVMLSVNVGILVGYIIGTHLPYYS------IPLMVLILPLWYLISVLLFIK 199
            ||::..::|||..:...|.:..||.:||........||      :||.:......::|..:.|:.
Yeast   193 SEVSPKHLRGTLVSCYQLMITAGIFLGYCTNFGTKNYSNSVQWRVPLGLCFAWALFMIGGMTFVP 257

  Fly   200 ESPMHLIRIGKYSAAERSFRYYKNIKDSDNIH-DQNRAMEEFEIMKIALTKGDALQDAVTFKDFY 263
            |||.:|..:||...|:||      |..|:.:. |....:.|.|.: :|..:.:.|....::.:.:
Yeast   258 ESPRYLAEVGKIEEAKRS------IAVSNKVAVDDPSVLAEVEAV-LAGVEAEKLAGNASWGELF 315

  Fly   264 S--RPALKAYGPALVLLIANQFSGLFTMVNYMSDIFANSGSTMDPDTCTIIIGAVQILGTYVTTL 326
            |  ...|:......::....|.:|......|.:.||...|.: |....:|::|.|....|:|...
Yeast   316 SSKTKVLQRLIMGAMIQSLQQLTGDNYFFYYGTTIFKAVGLS-DSFETSIVLGIVNFASTFVGIY 379

  Fly   327 LCDICGRKLLMLVSTGGVAISLTAFGFFTKYAESHNIGEYSWIP---------------LLLMSM 376
            :.:..||:..:|..    |.|:||  ....||   ::|.....|               ::....
Yeast   380 VVERYGRRTCLLWG----AASMTA--CMVVYA---SVGVTRLWPNGQDQPSSKGAGNCMIVFACF 435

  Fly   377 DIFLGNIGLVGCF--------FVSLVEMFPVKIRAKAASMAIVVCSIFVFLMLNIFPICMKQWGI 433
            .||        ||        :|.:.|.||:::::||.|:|.....::.||:....|.      |
Yeast   436 YIF--------CFATTWAPIPYVVVSETFPLRVKSKAMSIATAANWLWGFLIGFFTPF------I 486

  Fly   434 SATMWSCAGVTALSSLYFTYF-----MKETKGKSM 463
            :..:....|...:..|.|.:|     :.||||.::
Yeast   487 TGAINFYYGYVFMGCLVFMFFYVLLVVPETKGLTL 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	98/430 (23%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	95/433 (22%)
HXT7	NP_010629.3	Sugar_tr	68..528	CDD:395036	109/486 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342602
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13432
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.740