DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15408 and RGT2

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_010143.1	Gene:	RGT2 / 851417	SGDID:	S000002297	Length:	763	Species:	Saccharomyces cerevisiae

Alignment Length:	532	Identity:	114/532 - (21%)
Similarity:	210/532 - (39%)	Gaps:	127/532 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 NRYQL--------------LTTLLI--------NVISISHGIGI---GWL-------------SP 43
            |.||:              .|::|:        ||:|:..||.:   |:|             .|
Yeast    63 NAYQISYTNNEPAGDGAIETTSILLSQPLPLRSNVMSVLVGIFVAVGGFLFGYDTGLINSITDMP 127

  Fly    44 TLRKLQSDSPAGFEVKSEFEISWVGSMLGMGSVTGNILIGCLLGRLGSKRCLL-----LIAIPHS 103
            .::...:.:.:.|...   :|:.:.|.|.:|:..|.::...:....|.|..::     :.:|.:|
Yeast   128 YVKTYIAPNHSYFTTS---QIAILVSFLSLGTFFGALIAPYISDSYGRKPTIMFSTAVIFSIGNS 189

  Fly   104 CFWILVYFAQSVEYLYVGRLLAGICGGGMYIVHPILLSEIADANIRGTFSAMVMLSVNVGILVGY 168
                |...:..:..|.|||:::||..|.:..|.|:..:|.|..|:||...:....::.:|:||..
Yeast   190 ----LQVASGGLVLLIVGRVISGIGIGIISAVVPLYQAEAAQKNLRGAIISSYQWAITIGLLVSS 250

  Fly   169 II--GTHL----PYYSIPLMVLILPLWYLISVLL-----FIKESPMHLIRIGKYSAAERSFRYYK 222
            .:  |||.    ..|.||     :.|.|:.|.:|     |:.|||.:.:...:.:.|.:|..:.:
Yeast   251 AVSQGTHSKNGPSSYRIP-----IGLQYVWSSILAVGMIFLPESPRYYVLKDELNKAAKSLSFLR 310

  Fly   223 NIKDSDNIHDQNRAMEEFEIMKIALTKG-------DALQDAVTFKDFYSRP----------ALKA 270
            .:...|     .|.:|  |:::|..|..       ..|.|.  ||...:||          |::|
Yeast   311 GLPIED-----PRLLE--ELVEIKATYDYEASFGPSTLLDC--FKTSENRPKQILRIFTGIAIQA 366

  Fly   271 YGPALVLLIANQFSGLFTMVNYMSDIFANSGSTMDPDTCTIIIG-----AVQILGTYVTTLLCDI 330
            :         .|.||:..:..|..:.|.|:|  :|.......|.     |..|.|.|    |.|.
Yeast   367 F---------QQASGINFIFYYGVNFFNNTG--VDNSYLVSFISYAVNVAFSIPGMY----LVDR 416

  Fly   331 CGRKLLMLVSTGGVAISLTAFGF-FTKYAESHN-IGEYSWIPLLLMSMDIFLGNIGLVGCFFVSL 393
            .||:.::|  .|||.:::..... ....:|... :.....|..:.:.:..|....|  |..:|..
Yeast   417 IGRRPVLL--AGGVIMAIANLVIAIVGVSEGKTVVASKIMIAFICLFIAAFSATWG--GVVWVVS 477

  Fly   394 VEMFPVKIRAKAASMAIVVCSIFVFLMLNIFPICMKQWGISATM-------WSCAGVTALSSLYF 451
            .|::|:.:|:|..::......:..|....|.|..:.....:::|       |....|.|:..:||
Yeast   478 AELYPLGVRSKCTAICAAANWLVNFTCALITPYIVDVGSHTSSMGPKIFFIWGGLNVVAVIVVYF 542

  Fly   452 TYFMKETKGKSM 463
            ..:  ||:|.::
Yeast   543 AVY--ETRGLTL 552

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	102/470 (22%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	97/441 (22%)
RGT2	NP_010143.1	SP	76..555	CDD:273317	111/519 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342450
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9181
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.840