DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15408 and SNF3

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_010087.1	Gene:	SNF3 / 851333	SGDID:	S000002353	Length:	884	Species:	Saccharomyces cerevisiae

Alignment Length:	498	Identity:	102/498 - (20%)
Similarity:	197/498 - (39%)	Gaps:	71/498 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 LFQRPNCLLNRRNRYQLLTTLLINVISISHGIGIGWLSPTLRKLQSDSPAGFEVKSEF------- 62
            ||..|      ..:..::.::.:.|.....|...|:.:..:..:.|.:    .|||..
Yeast    84 LFSEP------PQKQSMMMSICVGVFVAVGGFLFGYDTGLINSITSMN----YVKSHVAPNHDSF 138

  Fly    63 ---EISWVGSMLGMGSVTGNILIGCLLGRLGSKRCLL-----LIAIPHSCFWILVYFAQSVEYLY 119
               ::|.:.|.|.:|:..|.:....:....|.|..::     :.:|.:|    |...|..:..|.
Yeast   139 TAQQMSILVSFLSLGTFFGALTAPFISDSYGRKPTIIFSTIFIFSIGNS----LQVGAGGITLLI 199

  Fly   120 VGRLLAGICGGGMYIVHPILLSEIADANIRGTFSAMVMLSVNVGILVGYII--GTH----LPYYS 178
            |||:::||..|.:..|.|:..:|....::||...:....::..|:||...:  |||    ...|.
Yeast   200 VGRVISGIGIGAISAVVPLYQAEATHKSLRGAIISTYQWAITWGLLVSSAVSQGTHARNDASSYR 264

  Fly   179 IPLMVLILPLWYLISVLLFIKESPMHLIRIGKYSAAERSFRYYKNIKDSDNIHDQNRAMEEFEIM 243
            ||:.:..:...:|...:.|:.|||.:.:...|...|.:|..:.:.:.    :||.....|..||.
Yeast   265 IPIGLQYVWSSFLAIGMFFLPESPRYYVLKDKLDEAAKSLSFLRGVP----VHDSGLLEELVEIK 325

  Fly   244 KIALTKGDALQDAVTFKDFY----SRP--ALKAYGPALVLLIANQFSGLFTMVNYMSDIFANSGS 302
              |....:|...:..|.|.:    |||  .|:.: ..:.|....||||: ..:.|....|.|...
Yeast   326 --ATYDYEASFGSSNFIDCFISSKSRPKQTLRMF-TGIALQAFQQFSGI-NFIFYYGVNFFNKTG 386

  Fly   303 TMDPDTCTIIIGAVQILGTYVTTLLCDICGRKLLMLVSTGGVAISLTAF-----GFFTKYAESHN 362
            ..:....:.|..||.::.........:..||:.:::|  |||.:::..|     |...|...:..
Yeast   387 VSNSYLVSFITYAVNVVFNVPGLFFVEFFGRRKVLVV--GGVIMTIANFIVAIVGCSLKTVAAAK 449

  Fly   363 IGEYSWIPLLLMSMDIFLGNIGLVGCFFVSLVEMFPVKIRAKAASMAIVVCSIFVFLMLNIFPIC 427
            :    .|..:.:.:..|....|  |..:|...|::|:.:|:|..::......:..|:...|.|..
Yeast   450 V----MIAFICLFIAAFSATWG--GVVWVISAELYPLGVRSKCTAICAAANWLVNFICALITPYI 508

  Fly   428 MKQWGISATM-------WSCAGVTALSSLYFTYFMKETKGKSM 463
            :.....::::       |.......:..:|.|.:  ||||.::
Yeast   509 VDTGSHTSSLGAKIFFIWGSLNAMGVIVVYLTVY--ETKGLTL 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	89/424 (21%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	89/433 (21%)
SNF3	NP_010087.1	MFS_HXT	99..556	CDD:340914	99/477 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342451
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm13432
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	5	4.740