DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15408 and ESL1

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_849618.1	Gene:	ESL1 / 837413	AraportID:	AT1G08920	Length:	477	Species:	Arabidopsis thaliana

Alignment Length:	493	Identity:	115/493 - (23%)
Similarity:	209/493 - (42%)	Gaps:	78/493 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 LLNRRNRYQL---------LTTLLINVI-SISHGIGIGWLSPTLRKLQSDSPAGFEVKSEFEISW 66
            ||.|:|:..:         |.:..::|. |...|...|:.|.....:.:|  .|..|.   :.|.
plant    14 LLLRKNQNDINECRITAVVLFSTFVSVCGSFCFGCAAGYSSVAQTGIIND--LGLSVA---QYSM 73

  Fly    67 VGSMLGMGSVTGNILIGCLLGRLGSKRCLLLIAIPHSCFWILVYFAQSVEYLYVGRLLAGICGGG 131
            .||::..|.:.|.|..|.:...:|.|..:....|.....|:.|..|:...:|.:|||..|...|.
plant    74 FGSIMTFGGMIGAIFSGKVADLMGRKGTMWFAQIFCIFGWVAVALAKDSMWLDIGRLSTGFAVGL 138

  Fly   132 MYIVHPILLSEIADANIRGTFSAMVMLSVNVGILVGYIIGTHLPYYSIPLMVLILPLWYLISVLL 196
            :..|.|:.::||...::||.|.....|..:.|:.:.|:||..:.:.::.|:.|| |....:..|.
plant   139 LSYVIPVYIAEITPKHVRGAFVFANQLMQSCGLSLFYVIGNFVHWRNLALIGLI-PCALQVVTLF 202

  Fly   197 FIKESPMHLIRIGKYSAAERSFRYYKNIKDSDNIHDQNRAMEEFEIMKIALTKGDALQDAVTFKD 261
            ||.|||..|.:.|.......|.:..:.  |..:|.::...::|..|:.....|...:       |
plant   203 FIPESPRLLGKWGHEKECRASLQSLRG--DDADISEEANTIKETMILFDEGPKSRVM-------D 258

  Fly   262 FYSRPALKAYGPALV----LLIANQFSGLFTMVNYMSDIFANSGSTMDPDTC-TIIIGAVQILGT 321
            .:.|    .|.|::|    |::..|.||...::.|:..:|...|.   |.:. ::|:..:.|...
plant   259 LFQR----RYAPSVVIGVGLMLLQQLSGSSGLMYYVGSVFDKGGF---PSSIGSMILAVIMIPKA 316

  Fly   322 YVTTLLCDICGRKLLMLV-------STGGVAI--SLTAFGF-FTKYAESHNIGEYSWIPLLLMSM 376
            .:..:|.:..||:.|:|:       ||||:..  .|.:|.| |..|.            :|....
plant   317 LLGLILVEKMGRRPLLLMNDLYLQASTGGMCFFSLLLSFSFCFRSYG------------MLDELT 369

  Fly   377 DIF--LGNIGLVGCF--------FVSLVEMFPVKIRAKAASMAIVVCSIFVFLMLNIFPICMKQW 431
            .||  :|.:|.:..|        ::.:.|:||:.::..|.::..:....|.:::...:.. |.:|
plant   370 PIFTCIGVVGFISSFAVGMGGLPWIIMSEIFPMNVKVSAGTLVTLANWSFGWIVAFAYNF-MLEW 433

  Fly   432 GISAT---MWSCAGVTALSSLYFTYFM-KETKGKSMLD 465
            ..|.|   .::..|    :.:.|.|.| .||||:::.|
plant   434 NASGTFLIFFTICG----AGIVFIYAMVPETKGRTLED 467

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	98/427 (23%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	96/422 (23%)
ESL1	NP_849618.1	Sugar_tr	36..469	CDD:278511	110/471 (23%)
ESL1	NP_849618.1	MFS	36..457	CDD:119392	104/459 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.930