Protein Alignment CG15408 and SLC2A1

DIOPT Version :9

• Sequence 1: NP_608767.1
• Gene: CG15408 / 33548
• FlyBaseID: FBgn0031523
• Length: 466
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 479
• Identity: 109/479 - (22%)
• Similarity: 188/479 - (39%)
• Gaps: 119/479 - (24%)

  Fly    34 HGIGIGWLSPTLRKLQSDSPAGFEVKSEFEISWVGSMLGMGSVTGNILIGCLLGRLGSKRCLLLI 98
            |..|...|..||..|.|.|.|.|.|               |.:.|:..:|..:.|.|.:..:|::
Human    50 HRYGESILPTTLTTLWSLSVAIFSV---------------GGMIGSFSVGLFVNRFGRRNSMLMM 99

  Fly    99 AIPHSCFWILVYFA---QSVEYLYVGRLLAGI-CGGGMYIVHPILLSEIADANIRGTFSAMVMLS 159
            .:......:|:.|:   :|.|.|.:||.:.|: ||.....| |:.:.|::...:||....:..|.
Human   100 NLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFV-PMYVGEVSPTALRGALGTLHQLG 163

  Fly   160 VNVGILVGYIIGT-----HLPYYSIPLMVLILPLWYLISVLLFIKESPMHLIRIGKYSAAERSFR 219
            :.||||:..:.|.     :...:.:.|.::.:|......||.|..|||..|: |.: :...|:..
Human   164 IVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLL-INR-NEENRAKS 226

  Fly   220 YYKNIK-DSDNIHDQNRAMEEF-EIMKIALTKGDALQDAVTFKDFYSRPALKAYGP---ALVLLI 279
            ..|.:: .:|..||.....||. ::|:         :..||..:.:..||.:.  |   |:||.:
Human   227 VLKKLRGTADVTHDLQEMKEESRQMMR---------EKKVTILELFRSPAYRQ--PILIAVVLQL 280

  Fly   280 ANQFSGLFTMVNYMSDIFANSGSTMDPDTCTIIIGAVQILGTYVTTLLCDICGRKLLMLVSTGGV 344
            :.|.||:..:..|.:.||..:| ...|...||..|.|....|.|:..:.:..||:.|.|:...|:
Human   281 SQQLSGINAVFYYSTSIFEKAG-VQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGM 344

  Fly   345 ---AISLTAFGFFTKYAESHNIGEYSWIPLLLMSMDIFLGNIGLVGCF-FVSLVEMFPVKI---- 401
               ||.:|                   |.|.|:....::..:.:|..| ||:..|:.|..|
Human   345 AGCAILMT-------------------IALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFI 390

  Fly   402 -------RAKAASMAIV--------------------VCSIFVFLMLNIFPICMKQWGISATMWS 439
                   ..:.|::|:.                    :|..:||::..:..:..
Human   391 VAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLF----------- 444

  Fly   440 CAGVTALSSLYFTYF-MKETKGKS 462
                     ..|||| :.||||::
Human   445 ---------FIFTYFKVPETKGRT 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	97/404 (24%)
		MFS	60..455	CDD:119392	94/444 (21%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	108/476 (23%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:24847886	282..288		3/5 (60%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144106
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840