DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15408 and slc2a2

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001011453.1	Gene:	slc2a2 / 496943	XenbaseID:	XB-GENE-486462	Length:	495	Species:	Xenopus tropicalis

Alignment Length:	517	Identity:	129/517 - (24%)
Similarity:	213/517 - (41%)	Gaps:	126/517 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 RNRYQLLTTLLINVI-----SISHGIGIGWLSPTLRKL--------------QSD-SPAGFEVKS 60
            :.:..|..||:..|.     |:..|.|||.::...:.:              |:| :|....||.
Frog     2 KQQKNLTGTLVFAVFTAVLASLQFGYGIGVINAPQKIIENHYTRVLLEGSENQTDTTPVQSSVKM 66

  Fly    61 EFEISWVGSMLGMGSVTGNILIGCLLGRLGSKRCLL---LIAIPHSCFWILVYFAQSVEYLYVGR 122
            .:.:|  .|:..:|.:..:..:|.:..:||..:.::   ::|:..:....|....|:...:..||
Frog    67 YWSLS--VSVFSLGGMVSSFFVGWIADKLGRIKAMMVVNILAVIGALLMGLAPLGQAHALVIAGR 129

  Fly   123 LLAGI-CGGGMYIVHPILLSEIADANIRGTFSAMVMLSVNVGILVGYIIGTHLPYYSIPLMVLIL 186
            |:.|: ||....:| |:.:.||:...:||....:..|::..|||:..::|......|..|..::|
Frog   130 LITGLYCGLASGLV-PMYVGEISPTALRGALGTLHQLAIVTGILISQVVGLEFILGSEHLWPVLL 193

  Fly   187 PLWYLISV-----LLFIKESPMH-LIRIGKYSAAERSFRYYKNIKD-SDNIHDQNRAMEEFEIMK 244
            .|..:.:|     |.|..|||.. ||::||..||:|:....:...| :.:|.:..:..||.|..|
Frog   194 GLSGVPAVVQTILLFFCPESPRFLLIKLGKTEAAKRNLIKLRGEYDPTKDIEEMKKEKEEAESEK 258

  Fly   245 IALTKGDALQDAVTFKDF-YSRPALKAYGPALVLLIANQFSGLFTMVNYMSDIFANSGSTMDPDT 308
                |...:|   .||.. |.:|.:    .:|||.|:.||||:..:..|.:.||..:|.: .|..
Frog   259 ----KVSIIQ---LFKSSNYRQPLV----VSLVLHISQQFSGINGIFYYSTSIFTRAGIS-QPVY 311

  Fly   309 CTIIIGAVQILGTYVTTLLCDICGRKLLMLVSTGGV---AISLTAFGFFTKYAESHNIGEYSWIP 370
            .||.:|||..:.|.|:..|.:..||:.|.||..||:   ||.:|                   |.
Frog   312 ATIGVGAVNTVFTVVSVFLVEKAGRRSLYLVGLGGMCICAIVMT-------------------IA 357

  Fly   371 LLLMSMDIFLGNIGLVGCF-FVSLVEMFPVKI-----------RAKAASMAIVVCSIFVFLMLNI 423
            |.|::...::..:.||..| ||...|:.|..|           ..:.|:||:..|
Frog   358 LALLTQHAWMSYLSLVAIFLFVVFFEVGPGPIPWFIVAELFSQGPRPAAMAVSGC---------- 412

  Fly   424 FPICMKQWGISATMWSCAGVTALSSLY----------------------FTYF-MKETKGKS 462
               |         .|:|..:..:...|                      |||| :.||||||
Frog   413 ---C---------NWTCNFIIGMCFEYIADACGPYIFIIFAVLLLIFTVFTYFKVPETKGKS 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	113/439 (26%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	109/444 (25%)
slc2a2	NP_001011453.1	Sugar_tr	14..470	CDD:278511	126/505 (25%)
slc2a2	NP_001011453.1	MFS	69..453	CDD:119392	107/439 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010