DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15408 and slc2a5

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001008187.1	Gene:	slc2a5 / 493549	XenbaseID:	XB-GENE-494009	Length:	517	Species:	Xenopus tropicalis

Alignment Length:	488	Identity:	117/488 - (23%)
Similarity:	206/488 - (42%)	Gaps:	78/488 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 TTLLINVI-----SISHGIGIGWLSPTLRKLQSDSPAGFEVKSEFEISWVGSML----------- 71
            |.:|:.::     |..:|..:.       .:.|.||...:..:...|..|||.|
Frog    20 TLILVTLVATFGSSFQYGYNVA-------SVNSPSPFMKDFYNSTNIERVGSPLEDAFLTLLWSL 77

  Fly    72 -----GMGSVTGNILIGCLLGRLGSKRCLLLIAIPHSCFWIL-------VYFAQSVEYLYVGRLL 124
                 .:|...|::|:|.|:.:||.|..||.    ::.|.|:       ...|::.|.:...||.
Frog    78 TVSLYPLGGFFGSLLVGPLVSKLGRKGTLLF----NNIFSIIPAILMGTSVVAKTFEVIIASRLF 138

  Fly   125 AGICGGGMYIVHPILLSEIADANIRGTFSAMVMLSVNVGILVGYIIGTHLPYYSI------PLMV 183
            .|:|.|....|.|:.:.|::..|:||....|..|.:.||||:..|.|..   |.:      |:::
Frog   139 VGVCAGLSSNVVPMYVGEMSPKNLRGAIGIMPQLMITVGILMAQIFGIR---YILGNTEGWPILL 200

  Fly   184 LI--LPLWYLISVLLFIKESPMH-LIRIGKYSAAERSFRYYKNIKDSDNIHDQNRAMEEFEIMKI 245
            .:  :|....::.|.|..|||.: |:..|....|:::.:..:..:|.|     :...|.::..:.
Frog   201 ALTGIPAVLELAFLPFFPESPRYTLLHKGNEDKAKKALQRLRGWEDVD-----SEIKEMYQEDQS 260

  Fly   246 ALTKGD-ALQDAVTFKDFYSRPALKAYGPALVLLIANQFSGLFTMVNYMSDIFANSGSTMDPDT- 308
            ...:|. ::::..||     ||........:|:.:..|.||:..:..|...|:.::|  :..:|
Frog   261 EKAEGQLSVRNLCTF-----RPLRWQLISIIVMNMGQQLSGINAVYYYADSIYKSAG--VKEETI 318

  Fly   309 --CTIIIGAVQILGTYVTTLLCDICGRKLLMLVSTGGVAISLTAFGFFTKYAESHNIGEYSWIPL 371
              .|:..|:|.:|.|.....:.|..||::|:|...|...||.........|..:     .||:|.
Frog   319 QYVTVATGSVNVLMTLAAVFIVDSWGRRVLLLSGFGTCCISCVVLTIALVYQTT-----VSWMPY 378

  Fly   372 LLMSMDIF--LGN-IGLVGCFFVSLVEMFPVKIRAKAASMAIVVCSIFVFLMLNIFPICMKQWGI 433
            |.::..|.  :|: ||.....:|...|||....|..|..:|..|..:..|::..||...|.  |:
Frog   379 LSIACIIIYVIGHAIGPSPIPYVITTEMFRQASRPAAFMIAGSVHWLSNFIIGLIFEFLMN--GL 441

  Fly   434 SATMWSCAGVTALSSLYFTYF-MKETKGKSMLD 465
            .|..:.......|::..|.|. :.|||||:.|:
Frog   442 GAYCFILFAAICLATFIFIYIVVPETKGKTFLE 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	100/430 (23%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	104/434 (24%)
slc2a5	NP_001008187.1	MFS_GLUT_Class2	24..475	CDD:340990	115/484 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910