DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15408 and Slc2a7

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_017175793.1	Gene:	Slc2a7 / 435818	MGIID:	3650865	Length:	553	Species:	Mus musculus

Alignment Length:	502	Identity:	118/502 - (23%)
Similarity:	191/502 - (38%)	Gaps:	129/502 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 WLSPTL----RKLQSDSPAGFEVKSEFE------------------ISW--VGSMLGMGSVTGNI 80
            |||..:    |:.|..|..|.:|...|.                  :.|  ..||..:|.:.|::
Mouse    69 WLSLPVWLQHRRDQHTSQGGHKVLKSFYNDTHFERHGTFMDESTLLLLWSCTVSMFPLGGLLGSL 133

  Fly    81 LIGCLLGRLGSKRCLLL---IAIPHSCFWILVYFAQSVEYLYVGRLLAGICGGGMYIVHPILLSE 142
            ::|.::.:.|.|..||:   .||..:....:...|::.|.:.:.|:|.|||.|..|...|:.|.|
Mouse   134 VVGLMVNKWGRKGTLLINNVFAITSAVLMGVSKVARAFELIILSRVLVGICAGIAYSTLPMYLGE 198

  Fly   143 IADANIRGTFSAMVMLSVNVGILVGYIIGTH------------LPYYSIPLMVLILPLWYLISVL 195
            :|..|:||....|..:.|.:|:|:..|....            |....:|.::.:|.       |
Mouse   199 LAPQNLRGALGTMTEVFVIIGVLLAQIFSLQAILGNATGWPILLALTGVPAVIQLLS-------L 256

  Fly   196 LFIKESPMH-LIRIGKYSAAERSFRYYKNIKDSDNIHDQNRAME-EFEIMKIALTKGDALQDAVT 258
            .|..|||.: ||..|....|.::.|         .:..||..:| |.|.|:.......|......
Mouse   257 PFFPESPRYTLIEKGDEETARQALR---------RLRGQNYNVEAEMEEMRTEERTEQAEGRLSV 312

  Fly   259 FKDFYSRPALKAYGPALVLLIANQFSGLFTMVNYMSDIFANSGSTMDP---DTCTIIIGAVQILG 320
            ...|..||........:||:...|.||: ..|||.:|:...|.. :||   ...|:..|.:.::.
Mouse   313 LNLFTFRPLRWQLISIVVLMAGQQLSGI-NAVNYYADVIYTSAG-VDPTQSQYVTLGSGVINLVM 375

  Fly   321 TYVTTLLCDICGRKLLMLVSTGGVAISLTAFGFFT---------------------KYAESHNIG 364
            |.|:.::.:..||::|:|   .|.||..:|....|                     .|...|:||
Mouse   376 TLVSAVIIERLGRRILLL---SGYAICCSACLVLTVALLLQSTAPELSYLSIVCVFSYIVGHSIG 437

  Fly   365 EYSWIPLLLMSMDIFL-----------GNIGLVGCFFVSLVEMFPVKIRAKAASMAIVVCSIFVF 418
            . |.:|.::.: :|.|           |.:..:..|.|.|.  ||      :..:||...|..||
Mouse   438 P-SPVPSVVRT-EIVLQSSRTAAFTVDGAVHWLTNFIVGLT--FP------SIQVAIGAYSFLVF 492

  Fly   419 LMLNIFPICMKQWGISATMWSCAGVTALSSLYFTYFMKETKGKSMLD 465
                                  |||..|::.|....:.||||::.::
Mouse   493 ----------------------AGVCILTAAYIYVVIPETKGRTFVE 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	104/445 (23%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	106/466 (23%)
Slc2a7	XP_017175793.1	MFS_GLUT_Class2	89..518	CDD:340990	111/482 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834171
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850