DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15408 and CG32053

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_729587.1	Gene:	CG32053 / 39178	FlyBaseID:	FBgn0052053	Length:	496	Species:	Drosophila melanogaster

Alignment Length:	505	Identity:	106/505 - (20%)
Similarity:	199/505 - (39%)	Gaps:	115/505 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 PNCLLNRRNRYQLLTTLLINVISISHGIGIGWLSPTLRKLQSDSP-AGFEVKSEFEISW-VGSML 71
            |.|..:.||:.|........:|.::.|:.|.|      .:..||. :..||.:..:|.| :|:::
  Fly    44 PCCNRDLRNQPQANAVGAAALIFLTGGVHIAW------SIGFDSSLSELEVTNHVQICWFIGAII 102

  Fly    72 GMGSVTGNILIGCLLGRLGSKRCLL----LIAIPHSCFWILVYFAQSVEYLYVGRLLAGICGGGM 132
            |       .|:|....|....:.|:    ||.|....  ::......::.|..||.:.|:..|
  Fly   103 G-------ALLGGFFSRWFPYKTLMEFCSLITITGGI--VMAVNRMDLDALLAGRYMNGLANG-- 156

  Fly   133 YIVHPIL--LSEIADANIRG-TFSAMVMLSVNVGILVGYIIG---------THLPYYSIPLMVL- 184
            ..:.|.|  ..|::....|| |.||.......:||.|..:..         |...:..:...||
  Fly   157 LAIAPTLAMAGELSVFYKRGTTTSAAEQWPTTIGIFVQIVCSHSWDVQSDFTEEQFQGVLSGVLG 221

  Fly   185 --ILPLWYLISVLLFIKESPMHLIRIGKYSAAERSF-----------RYYKNIKDSDNIHDQNRA 236
              .|.|.:|:|:     |||:.|:..|....|.::.           ..|..::|.....:.:|:
  Fly   222 SIALLLAFLLSI-----ESPVDLLEQGNEQGAVQALSRLQRPRAVTAETYDQVRDHRTYVEHHRS 281

  Fly   237 MEEFEIMKIALTKGDALQDAVTFKDFYSRPALKAYGPALVLLIANQFSGLFTMVNYMSDIFANSG 301
            |.....:. ||.:...|:            ||  |..:|.:::|      ||:....::::.:|.
  Fly   282 MGWRHALP-ALVRLSVLR------------AL--YALSLSVMVA------FTLAWTSTEVYGDSS 325

  Fly   302 STMDPDTCTIIIGAVQILGTYVTTLLCDICGRKLLMLVSTGGVAIS-LTAFGFFTKYAESHNIGE 365
            ...      ::.|.::::|::.|:...|..|||:.:|:   |:.|| ..|.|..:::|.||.: .
  Fly   326 GPY------VLFGFLRLMGSFTTSFALDSLGRKIPLLL---GLVISGCLACGLASRFAGSHPL-T 380

  Fly   366 YS------WIPLLLMSMDIFLGNIGLVGCFFVSLVEMFPVKIRAKAASMAIVVCSIFVFLMLNIF 424
            :|      |   ||:...:|.|........::|  |.||.:|:..        |....:::..|.
  Fly   381 FSGNRMALW---LLLIYQLFAGIAFAPSSSYLS--EAFPRRIKRP--------CIAITYILEIIV 432

  Fly   425 PICMKQWGISAT----------MWSCAGVTALSSLYFTYFMKETKGKSML 464
            .:.::|...:|.          .:...|:.....|:..::|.|||..::|
  Fly   433 QLLLRQMDFAAIGSDSSYVALYFFILGGLLLAGFLFSVWYMPETKDTTLL 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	92/431 (21%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	88/442 (20%)
CG32053	NP_729587.1	MFS	73..428	CDD:119392	89/420 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444434
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740