DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15408 and CG14160

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_648380.2	Gene:	CG14160 / 39177	FlyBaseID:	FBgn0036066	Length:	483	Species:	Drosophila melanogaster

Alignment Length:	499	Identity:	104/499 - (20%)
Similarity:	191/499 - (38%)	Gaps:	110/499 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RYQLLTTLLINVISISHGIGIGWLSPTLRKLQSDSPAGFEVKS----EFEISW-----VGSMLG- 72
            |.|..:....:::.:..|:.:.|..       .|:|||..:.:    ...:||     ||::|.
  Fly    23 RLQFQSMASASIVFVGCGMRLAWSI-------FDTPAGKFLNNHNTHNLMMSWFIGAAVGALLAA 80

  Fly    73 --MGSVTGNILI---GCLLGRLGSKRCLLLIAIPHSCFWILVYFAQSVEYLY-VGRLLAGICGGG 131
              :..||.|:..   |.|:...|    :|.:.:|.. |....|.:.||...| :.::.|.:.|
  Fly    81 LFVQRVTKNVAYTSSGFLMIIAG----ILNVVLPQH-FLAACYSSVSVGAAYGLTQIQALVTG-- 138

  Fly   132 MYIVHPILLSEIADANIRGTFSAMVMLSVNVGILVGYIIGTHLPYYSIPL--------------M 182
                     ||:|..:|||...:...:.:.:|:.: .:..|.:.:...||              |
  Fly   139 ---------SEVAHKSIRGMLLSCEKIFLWLGVCM-QVFYTRVWHNLRPLDTQGYEMHIDQLHGM 193

  Fly   183 VLI-LPLWYLISVLLFIKESPMHLIRIGKYSAAERSFRYYKNIK---------------DSDNIH 231
            ||. |.|..:|..|....|||:.|:.      .||.....:.:|               |...:|
  Fly   194 VLAGLGLGAVILALAHRLESPLLLLH------QERDMAVGETLKALHGQSTTELVRLREDCRQLH 252

  Fly   232 ---DQNRAMEEFEIMKIALTKGDALQDAVTFKDFYSRPALKAYGPALVLLIANQFSGLFTMVNYM 293
               |..|.:||.|             ::|.....::|..|    |...:|:...|:.|...::|.
  Fly   253 SARDWERFVEEPE-------------ESVADWRVWARRIL----PFFKVLLLRCFATLAVSLSYN 300

  Fly   294 SDIFANSGSTMDPD-TCTIIIGAVQILGTYVTTLLCDICGRKLLMLVS--TGGVAISLTAFGFFT 355
            ......|...::.| .|...:....::|:.:...:.|..||:.:..:|  ..||.|.:.. |.|
  Fly   301 RAFVVVSWHGLECDMNCMYWLAFAGLIGSVLGAFVVDWQGRRKVCSLSLFLAGVVIVMVG-GVF- 363

  Fly   356 KYAESHNIGEYSWIPLLLMSMDIFLGNIGLVGCFFV-SLV---EMFPVKIRAKAASMAIVVCSIF 416
            .:.||.....|. |.||::::.:.|..:.:.|...| :||   |.|.:..:|:..:..::|..:
  Fly   364 DHLESVKRSFYD-INLLVIALLMLLFEVIVAGGVAVPALVYTAEAFSIAHKARCLAGILIVEQL- 426

  Fly   417 VFLMLNIFPICMKQWGISATMWSCAGV-TALSSLYFTYFMKETK 459
              |.|.:.....:.:...:..:...|| :.:..|....||.||:
  Fly   427 --LQLGLLLATFEHYITVSVFFFTIGVFSFIVGLTVFMFMPETR 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	94/447 (21%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	92/451 (20%)
CG14160	NP_648380.2	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444438
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740