DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15408 and CG32054

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_729588.1	Gene:	CG32054 / 326185	FlyBaseID:	FBgn0052054	Length:	563	Species:	Drosophila melanogaster

Alignment Length:	502	Identity:	102/502 - (20%)
Similarity:	185/502 - (36%)	Gaps:	127/502 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 NRRNRYQLLTTLLINVISISHGIGIGWLSPTLRKLQSDSPAGFEVKSEFE------ISWVGSMLG 72
            |::|:.|........:|.:|.|:.|.|            ..||.....::      .:|.
  Fly   114 NQKNKPQSNAVGAAGLIFVSGGMNIAW------------SIGFRGVLHYKTTEHNFAAWF----- 161

  Fly    73 MGSVTGNILIGCLLGRLGSKRCLLLIAIPHSCFWILV------YFAQSVEYLYVGRLLAGICGGG 131
            :|.:.|.::...|:..:..|..|:.     |.|.:::      ....|.:.......|.||..|.
  Fly   162 IGGIIGAVISWFLINNVAKKYVLIF-----SSFLVMIGGILTTSTKNSGDATLAASYLDGIANGL 221

  Fly   132 MYIVHPILLSEIADANIRGTFSAMV-MLSVNVGILVGYII-----GTHLPYY---SIPLMVLILP 187
            ::.....|..|::.:.:||..||.: .:...:||.:..|.     .|..|.|   |...|..:|.
  Fly   222 VFAPFMALAGEVSVSYMRGMVSASIEQMCFGLGIFLQIIYTSTWNSTAYPSYNSFSAENMKGVLS 286

  Fly   188 LWY-----LISVLLFIKESPMHLI-----RIGKYSAAERSFRYYKNIKDS-DNIHDQNRAMEEFE 241
            :.|     :|..||.| |||:.::     ..|...|..|..|.|....:: :.:.:..:.:.:.:
  Fly   287 IIYGFLALIIGSLLCI-ESPVIMLAKNNDEQGAIDALRRLQRPYTLTNETFEQLAEHKKYLAQNK 350

  Fly   242 IMKIALTKGDALQDAVTFKDFYSRPALKAYGPALVLLI----ANQFS-GLFTMVNYMSDIFANSG 301
            .:.:..:.|.||                   |..:.|:    .|..| ..|.|:.::.. ||:..
  Fly   351 ELSMGQSIGQAL-------------------PTFIRLVFLRGLNAMSISKFVMIGFVYS-FASPY 395

  Fly   302 STMDPDTCTII-IGAVQILGTYVTTLLCDICGRK---LLMLVSTGGVAISLTA-FGFFTKYAESH 361
            ..:.|.....| .|..:.:|.::.|...:.||||   ||.|:....::..:.. |..|| |...:
  Fly   396 GYVSPSVGWFIGFGVCRWMGNFIATFCMESCGRKKPTLLGLIVCSVMSFVVAGQFNIFT-YNTGN 459

  Fly   362 NIGEYSWIPLLLMSMDIFLGNIGLVGCFFVS----LVEMFPVKIRAKAASMAIVVCSIFVFLMLN 422
            ||        :|:..::|      .|..|.:    |.|.||::::....|... :..:.|||:|.
  Fly   460 NI--------MLLVFELF------AGIAFTATSPYLSEAFPLEVKQHFISFTF-IGEMLVFLVLT 509

  Fly   423 IFPICMKQWGISATMWSCAG----VTALSSLY-FTYF-----MKETK 459
            :.            .||.:|    ...:..|| |.:|     :.||:
  Fly   510 LI------------RWSSSGGANYFYVMGGLYLFGFFFGLVCLPETR 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	88/438 (20%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	90/450 (20%)
CG32054	NP_729588.1	Pro-rich	<7..101	CDD:291893
CG32054	NP_729588.1	MFS	157..539	CDD:119392	90/440 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45444437
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740