DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15408 and Slc2a2

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_037011.2	Gene:	Slc2a2 / 25351	RGDID:	3705	Length:	522	Species:	Rattus norvegicus

Alignment Length:	481	Identity:	121/481 - (25%)
Similarity:	206/481 - (42%)	Gaps:	107/481 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 VISISHGIGIGWLSPT------LRKLQSDSPAGFEV---KSEFEISWVGSMLG---------MGS 75
            :::.:|.....|...|      :..|.|.|.:.|.|   .:.|...|:|..||         ..|
  Rat    69 IVTPAHTTPDAWEEETEGSAHIVTMLWSLSVSSFAVGGMVASFFGGWLGDKLGRIKAMLAANSLS 133

  Fly    76 VTGNILIGCLLGRLGSKRCLLLIAIPHSCFWILVYFAQSVEYLYVGRLLAGICGGGMYIVHPILL 140
            :||.:|:||  .:.|....|::.             .:||..||.| |::|:.        |:.:
  Rat   134 LTGALLMGC--SKFGPAHALIIA-------------GRSVSGLYCG-LISGLV--------PMYI 174

  Fly   141 SEIADANIRGTFSAMVMLSVNVGILVGYIIGT-----HLPYYSIPLMVLILPLWYLISVLLFIKE 200
            .|||...:||....:..|::..|||:..|.|.     :..|:.|.|.:..:|......:|||..|
  Rat   175 GEIAPTTLRGALGTLHQLALVTGILISQIAGLSFILGNQDYWHILLGLSAVPALLQCLLLLFCPE 239

  Fly   201 SPMHL-IRIGKYSAAERSFRYYKNIKD-SDNIHDQNRAMEEFEI-MKIALTKGDALQDAVTFKD- 261
            ||.:| :::.:...|::|.:..:..:| :.:|::..:..||... .|:::.:        .|.|
  Rat   240 SPRYLYLKLEEEVRAKKSLKRLRGTEDVTKDINEMRKEKEEASTEQKVSVIQ--------LFTDP 296

  Fly   262 FYSRPALKAYGPALVLLIANQFSGLFTMVNYMSDIFANSGSTMDPDTCTIIIGAVQILGTYVTTL 326
            .|.:|.:    .||:|.:|.||||:..:..|.:.||..:|.: .|...||.:||:.::.|.|:.|
  Rat   297 NYRQPIV----VALMLHLAQQFSGINGIFYYSTSIFQTAGIS-QPVYATIGVGAINMIFTAVSVL 356

  Fly   327 LCDICGRKLLMLVSTGGVAISLTAFGFFTKYAESHN---IGEYSWIPLLLMSMDIFLGNIGLVGC 388
            |.:..||:.|.|....|:        ||.....|..   :.:::|:..:.|:. |||
  Rat   357 LVEKAGRRTLFLAGMIGM--------FFCAVFMSLGLVLLDKFTWMSYVSMTA-IFL-------- 404

  Fly   389 FFVSLVEMFPVKI-------------RAKAASMAIV---VCSIFVFLMLNIFPICMKQWGISATM 437
             |||..|:.|..|             |..|.::|..   ||:..:.|........:..:    ..
  Rat   405 -FVSFFEIGPGPIPWFMVAEFFSQGPRPTALALAAFSNWVCNFIIALCFQYIADFLGPY----VF 464

  Fly   438 WSCAGVTALSSLYFTYF-MKETKGKS 462
            :..|||..:.:| ||:| :.||||||
  Rat   465 FLFAGVVLIFTL-FTFFKVPETKGKS 489

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	104/423 (25%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	107/432 (25%)
Slc2a2	NP_037011.2	MFS_GLUT_Class1	12..488	CDD:340989	118/478 (25%)
Slc2a2	NP_037011.2	Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	312..318		4/5 (80%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337872
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850