DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15408 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_006505885.1	Gene:	Slc2a3 / 20527	MGIID:	95757	Length:	495	Species:	Mus musculus

Alignment Length:	473	Identity:	120/473 - (25%)
Similarity:	196/473 - (41%)	Gaps:	78/473 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 VISISHGIGIGWLSPTLRKLQSDSPAGFEVKSEFEISWVGSM----LGMGSVTGNILIGCLLGRL 89
            ||:....|...:|:.||.:...|.|      ||..::.:.|:    ..:|.:.|:..:|..:.|.
Mouse    32 VINAPETILKDFLNYTLEERLEDLP------SEGLLTALWSLCVAIFSVGGMIGSFSVGLFVNRF 90

  Fly    90 GSKRCLLLI---AIPHSCFWILVYFAQSVEYLYVGRLLAGI-CGGGMYIVHPILLSEIADANIRG 150
            |.:..:||:   ||...|.......|:|||.|.:||||.|| ||.....| |:.:.|::...:||
Mouse    91 GRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGLCTGFV-PMYIGEVSPTALRG 154

  Fly   151 TFSAMVMLSVNVGILVGYIIGTHLPYYSIPLM-----VLILPLWYLISVLLFIKESPMHLIRIGK 210
            .|..:..|.:.|||||..|.|......|..|.     :.|:|.....:.|.|..|||..|:
Mouse   155 AFGTLNQLGIVVGILVAQIFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLL---- 215

  Fly   211 YSAAERSFRYYKNIKDSDNIHDQNRAMEEFEIMKIALTKGDALQDAVTFKD-------------- 261
                       .|.|:.|         :..||::......|.:|:....||
Mouse   216 -----------INKKEED---------QATEILQRLWGTSDVVQEIQEMKDESVRMSQEKQVTVL 260

  Fly   262 ------FYSRPALKAYGPALVLLIANQFSGLFTMVNYMSDIFANSGSTMDPDTCTIIIGAVQILG 320
                  .|.:|.|    .::||.::.|.||:..:..|.:.||.::| ..:|...||..|.|..:.
Mouse   261 ELFRSPNYVQPLL----ISIVLQLSQQLSGINAVFYYSTGIFKDAG-VQEPIYATIGAGVVNTIF 320

  Fly   321 TYVTTLLCDICGRKLLMLVSTGGVAISLTAFGFFTKYAESHNIGEYSWIPLLLMSMDIFLGNIGL 385
            |.|:..|.:..||:.|.::..||:|:............:.:....:..|..:|:.:..|....|.
Mouse   321 TVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKDDYEAMSFVCIVAILIYVAFFEIGPGP 385

  Fly   386 VGCFFVSLVEMFPVKIRAKAASMAIVVCSIFV--FLMLNIFPICMKQWGISATMWSCAGVTALSS 448
            :..|.|:  |:|....|  .|::|:..|..:.  ||:..:||......|  |.::.......:..
Mouse   386 IPWFIVA--ELFSQGPR--PAAIAVAGCCNWTSNFLVGMLFPSAAAYLG--AYVFIIFAAFLIFF 444

  Fly   449 LYFTYF-MKETKGKSMLD 465
            |.||:| :.||||::..|
Mouse   445 LIFTFFKVPETKGRTFED 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	103/413 (25%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	107/430 (25%)
Slc2a3	XP_006505885.1	MFS_GLUT_Class1	14..458	CDD:340989	118/467 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834197
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.840