DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15408 and slc2a9

DIOPT Version :9

Sequence 1:	NP_608767.1	Gene:	CG15408 / 33548	FlyBaseID:	FBgn0031523	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_002936818.2	Gene:	slc2a9 / 100495427	XenbaseID:	XB-GENE-5883703	Length:	514	Species:	Xenopus tropicalis

Alignment Length:	472	Identity:	99/472 - (20%)
Similarity:	193/472 - (40%)	Gaps:	98/472 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 DSPAGFEVKSEFEISW-------------------VGSMLGMGSVTGNILIGCLLGRLGSKRCLL 96
            :||:.: :|:.:..:|                   ..|:..:|.:.|::|:|.|:.|.|.|..::
Frog    44 NSPSEY-IKAFYNTTWNQRYGEALEQSPLTLMYSLTVSVFALGGMLGSLLVGILVSRFGRKGTII 107

  Fly    97 ----LIAIPHSCFWILVYFAQSVEYLYVGRLLAGICGGGMYIVHPILLSEIADANIRGTFSAMVM 157
                |:.:......:...|: |.|.:.:||.:.||..|....|.|:.|.||:..|:||....:..
Frog   108 RSTPLVFVAGGLMGLSRIFS-SPEMVIIGRFITGIHSGISLSVVPMYLGEISPKNLRGLLGLVPS 171

  Fly   158 LSVNVGILVGYIIGTHLP-------YYSIPLMVLILPLWYLISVLLFIKESPMHLIRIGKYSAAE 215
            :.:.:|:....::|  ||       .:.:.|.::::|.:..:.:|.:..|||.:|
Frog   172 IFICLGVFSAQVLG--LPELLGQDETWPLFLSLVVVPTFVQLVLLPWFPESPRYL---------- 224

  Fly   216 RSFRYYKNIKDSDNIHDQNRAME----EFEIMKI-----ALTKGDALQDAVTFKDFYSRPALKAY 271
                    :.|..|:|....|:.    |:::..:     ...|..:..|.|:...|.|.|.|  :
Frog   225 --------LIDKSNVHGTIDALRCFLGEYDVQDVIEEMQEEQKSFSSVDTVSVCQFLSDPTL--F 279

  Fly   272 GPALVLLIAN---QFSGLFTMVNYMSDIFANSGSTMD--PDTCTIIIGAVQILGTYVTTLLCDIC 331
            ...|.:::.|   |.||:..:..|.:.||.|:|..|.  |.| |:..||::|:...:.....:..
Frog   280 WQILSVIVINIGMQLSGIDAIWFYTNSIFENAGIPMAEIPYT-TVGTGAIEIVAGLIGCFTVEKL 343

  Fly   332 GRKLLML-------VSTGGVAISLTAFGFFTKYAESHNIGEYSWIPLL-LMSMDIFLG-----NI 383
            ||:.|::       ....|:.::|.   |..:            :|:: .:|:...:|     .|
Frog   344 GRRPLLIGGFSFMGFCCAGITLALV---FQAR------------VPVMRYVSVACVIGIIAGFCI 393

  Fly   384 GLVGCFFVSLVEMFPVKIRAKAASMAIVVCSIFVFLMLNIFPICMKQWGISATMWSCAGVTALSS 448
            |..|..|:...|:|....|..|..:...:..:..|.:..:||......|....|..| |:....:
Frog   394 GPAGLPFIITGELFTQSHRPAAFIVGGTLNWLSNFTVGFVFPFLQISAGAFCYMVFC-GICLFVA 457

  Fly   449 LYFTYFMKETKGKSMLD 465
            .|..|.:.|||.::.::
Frog   458 AYVYYIIPETKNRTFME 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15408	NP_608767.1	2A0115	17..410	CDD:273327	87/415 (21%)
CG15408	NP_608767.1	MFS	60..455	CDD:119392	93/451 (21%)
slc2a9	XP_002936818.2	MFS_GLUT_Class2	30..475	CDD:340990	99/472 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910