DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and HXT8

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_012321.1	Gene:	HXT8 / 853216	SGDID:	S000003750	Length:	569	Species:	Saccharomyces cerevisiae

Alignment Length:	479	Identity:	116/479 - (24%)
Similarity:	194/479 - (40%)	Gaps:	98/479 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 LLNIATFSHGLGVGWMSPVMRDLQTDESPLDFPVLVSQVSWIGSLVGIGSVMGNLIAGLLMDRIG 95
            |.....:||.....::|.|...|                  |.|:..:||.:|.|....|.|..|
Yeast    97 LRRFGNYSHSKNTYYLSNVRTGL------------------IVSIFNVGSAIGCLFLSKLGDIYG 143

  Fly    96 RKMVLFFIAIPYTTFWCLIYFVQSVEFLY---IGRLMAGITGGACYVVLPTFISEIADTNVRGRL 157
            |.|.|..:.:.|..  .::..:.|::..|   |||::|||..|:..|:.|..|||.|..::||.|
Yeast   144 RCMGLIIVIVVYMV--GIVIQIASIDKWYQYFIGRIIAGIGAGSISVLAPMLISETAPKHIRGTL 206

  Fly   158 GSIILLSVNTGVLAGYIVS--TRVDYFTSPPFIIGLPVCYFICNFLI------PETPHHLVRKGK 214
            .:...|.|...:..||..:  |:. |..|..:.:.|.:|:.....:|      ||:|..||:.||
Yeast   207 LACWQLMVTFAIFLGYCTNYGTKT-YSNSVQWRVPLGLCFAWAIIMIGGMTFVPESPRFLVQVGK 270

  Fly   215 FEAAKRSFMFYKNIRKNDIKAEDE--FEEMKYLLIKEQTEKAK-SFDYRDFITRPAFKAYASAAV 276
            .|.||.||     .:.|.:..:|.  ..|:..|:...:.|:|. :..:::..:|.. |.:....:
Yeast   271 IEQAKASF-----AKSNKLSVDDPAVVAEIDLLVAGVEAEEAMGTASWKELFSRKT-KVFQRLTM 329

  Fly   277 LLISN---QFSASFCVTTYLADVFAASHTTLNLGM-----CTIIIGVLQIVGNYVTTLLCDKYGR 333
            .::.|   |.:.......|...:|.      ::||     .:|::|::.....:.:....||.||
Yeast   330 TVMINSLQQLTGDNYFFYYGTTIFK------SVGMNDSFETSIVLGIVNFASCFFSLYSVDKLGR 388

  Fly   334 RILMLTSTLGASVCLTAF---GTFTFFAEAADLSSVDWLP--LVILSC---FVFLCNIGLVGCLF 390
            |..:|......:.|:..:   |....:.......|.....  .::.:|   |.|.|..|.| | :
Yeast   389 RRCLLLGAATMTACMVIYASVGVTRLYPNGKSEPSSKGAGNCTIVFTCFYIFCFSCTWGPV-C-Y 451

  Fly   391 VVLVELFPAKIRS--VSVSTFVVILSSTVFLTLKIFPICMAVWGTSV---TMWSCSGITF----- 445
            |::.|.||.::||  :||:|...:|                 ||..:   |.:..|.|.|
Yeast   452 VIISETFPLRVRSKCMSVATAANLL-----------------WGFLIGFFTPFITSAINFYYGYV 499

  Fly   446 ------FSFLYFCFFLEETNGKSL 463
                  ||:.|..||:.||.|.:|
Yeast   500 FMGCLAFSYFYVFFFVPETKGLTL 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	105/446 (24%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	100/418 (24%)
HXT8	NP_012321.1	Sugar_tr	69..530	CDD:395036	116/479 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342523
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.740