DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3285 and MAL31

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_009857.1	Gene:	MAL31 / 852601	SGDID:	S000000502	Length:	614	Species:	Saccharomyces cerevisiae

Alignment Length:	498	Identity:	109/498 - (21%)
Similarity:	200/498 - (40%)	Gaps:	107/498 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 TLLLNIATFSHG-----LGVGWMSPVMR----DLQTDESPLDFPVLVSQVSWIGSLVGI------ 78
            :||::......|     ||..:..||.:    .|.::..  |:.:   .|||   .:|:
Yeast   103 SLLVSTTLIQEGYDTAILGAFYALPVFQKKYGSLNSNTG--DYEI---SVSW---QIGLCLCYMA 159

  Fly    79 GSVMGNLIAGLLMDRIGRK----MVLFFIAIPYTTFWCLIYFVQSVEFLYIGRLMAGITGGACYV 139
            |.::|..:.|..:|.:|.:    |.|||:|    .|..::||.:|:..:.:|:.:.|:..|....
Yeast   160 GEIVGLQMTGPSVDYMGNRYTLIMALFFLA----AFIFILYFCKSLGMIAVGQALCGMPWGCFQC 220

  Fly   140 VLPTFISEIADTNVRGRLGSIILLSVNTGVL--AGYIVSTRVDYFTSP-----PF----IIGLPV 193
            :..::.|||....:|..|.:...|....|.|  ||.:.:::..|..|.     ||    |..||:
Yeast   221 LTVSYASEICPLALRYYLTTYSNLCWAFGQLFAAGIMKNSQNKYANSELGYKLPFALQWIWPLPL 285

  Fly   194 CYFICNFLIPETPHHLVRKGKFEAAKRSF---MFYKNIRKNDIKAEDEFEEMKYLLIKEQ--TEK 253
            ...|  |..||:|..||:||:.:.|:||.   :..|...| ::....|.:::|..:.|||  :::
Yeast   286 AVGI--FFAPESPWWLVKKGRIDQARRSLERTLSGKGPEK-ELLVSMELDKIKTTIEKEQKMSDE 347

  Fly   254 AKSFD-YRDFITRPAFK---------AYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGM 308
            ...:| .:|.|.|...:         ....|:::..|..|.....|:|..|..|
Yeast   348 GTYWDCVKDGINRRRTRIACLCWIGQCSCGASLIGYSTYFYEKAGVSTDTAFTF----------- 401

  Fly   309 CTIIIGVLQIVGNYVTTLLCDKYGRRILMLTSTLGASVCLTAFGTFTFF---------AEAADLS 364
             :||...|.|...:: :....||..|..:....|       ||....||         ...|.:.
Yeast   402 -SIIQYCLGIAATFI-SWWASKYCGRFDLYAFGL-------AFQAIMFFIIGGLGCSDTHGAKMG 457

  Fly   365 SVDWLPLVILSCFVFLCNIGLVGCLFVVLVELFPAKIRSVSVSTFVVILSSTVFLTLKIFPICMA 429
            |.     .:|....|..|:|:...:|.::.|:..:::|     |..:||:...:..:::....:.
Yeast   458 SG-----ALLMVVAFFYNLGIAPVVFCLVSEIPSSRLR-----TKTIILARNAYNVIQVVVTVLI 512

  Fly   430 VWGTSVTMWSCSGITFFSFLYFCFF--------LEETNGKSLL 464
            ::..:...|:....:.|.:..||..        |.||.|::.:
Yeast   513 MYQLNSEKWNWGAKSGFFWGGFCLATLAWAVVDLPETAGRTFI 555

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	102/467 (22%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	99/440 (23%)
MAL31	NP_009857.1	SP	74..557	CDD:273317	109/498 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342472
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830