DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and STL1

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_010825.3	Gene:	STL1 / 852149	SGDID:	S000002944	Length:	569	Species:	Saccharomyces cerevisiae

Alignment Length:	538	Identity:	115/538 - (21%)
Similarity:	188/538 - (34%)	Gaps:	169/538 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LLGRRIRHQFLVTLLLNIATFSHGLGVGWMSPVMRDLQTDES-PLDFP-----------VLVSQV 69
            |.|:::|:...:..:...:.|.:..|      :|..|.|.:. ..:||           ..|.|.
Yeast    22 LTGKKLRYFITIASMTGFSLFGYDQG------LMASLITGKQFNYEFPATKENGDHDRHATVVQG 80

  Fly    70 SWIGSLVGIGSVMGNLIAGLLMDRIGRKMVLFFIAI-----------PYTTFWCLIYFVQSVEFL 123
            : ..|...:|...|:|......:|||||.::...::           .:..:|.|..|:
Yeast    81 A-TTSCYELGCFAGSLFVMFCGERIGRKPLILMGSVITIIGAVISTCAFRGYWALGQFI------ 138

  Fly   124 YIGRLMAGITGGACYVVLPTFISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSP--- 185
             |||::.|:..|.....:|.:.||::....||.|.::...::..|.:..|.:...:.|..|.
Yeast   139 -IGRVVTGVGTGLNTSTIPVWQSEMSKAENRGLLVNLEGSTIAFGTMIAYWIDFGLSYTNSSVQW 202

  Fly   186 --PFIIGLPVCYFICNFLI--PETPHHLVRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLL 246
              |..:.:....|:..|:|  ||:|..|:.:.:.|.|:.......:...||   |:...|:..|
Yeast   203 RFPVSMQIVFALFLLAFMIKLPESPRWLISQSRTEEARYLVGTLDDADPND---EEVITEVAML- 263

  Fly   247 IKEQTEKAKSFDYRDFITRPAFKAYA-------------SAAVLLISNQFSASF--C-VTTYLAD 295
                         .|.:.|...:.::             ..|::..|.||...|  | ...|.:.
Yeast   264 -------------HDAVNRTKHEKHSLSSLFSRGRSQNLQRALIAASTQFFQQFTGCNAAIYYST 315

  Fly   296 VFAASHTTLNLGMCTIIIGV------LQIVGNYVTTLLCDKYGRRILMLTSTLGASVCLT----- 349
            |.......|:..:..||.||      |..:|::   .|.:|.|||.|.|....|.:|..|
Yeast   316 VLFNKTIKLDYRLSMIIGGVFATIYALSTIGSF---FLIEKLGRRKLFLLGATGQAVSFTITFAC 377

  Fly   350 ------------AFGTF---TFFAEAADLSSVDWL-PLVILS------------CFVFLCNIGLV 386
                        |.|.|   |||  ...|.|:.|: |..|.|            |..:|||
Yeast   378 LVKENKENARGAAVGLFLFITFF--GLSLLSLPWIYPPEIASMKVRASTNAFSTCTNWLCN---- 436

  Fly   387 GCLFVVLVELFPAKIRSVSVSTFVVILSSTVFLTLKIFPICMAVWGTSVTMWSCSGITFF---SF 448
                                  |.|::.:.:|:            |.|  .|.|  ..||   ::
Yeast   437 ----------------------FAVVMFTPIFI------------GQS--GWGC--YLFFAVMNY 463

  Fly   449 LY---FCFFLEETNGKSL 463
            ||   ..||..||.|:||
Yeast   464 LYIPVIFFFYPETAGRSL 481

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	101/498 (20%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	96/471 (20%)
STL1	NP_010825.3	Sugar_tr	32..488	CDD:395036	112/528 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	3	2.810