DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3285 and ITR1

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_010785.1	Gene:	ITR1 / 852108	SGDID:	S000002905	Length:	584	Species:	Saccharomyces cerevisiae

Alignment Length:	492	Identity:	124/492 - (25%)
Similarity:	202/492 - (41%)	Gaps:	91/492 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FLVTL--LLNIATFSHGLGVGWMSPVMRDLQTDESPLDFPVLV-SQVSWIGSLVGIGSVMGNLIA 87
            |::||  :.:|:.|..|...|::|..:..:.||   ||..||. .:...:.:...:|:::.::.|
Yeast    85 FIITLTFVASISGFMFGYDTGYISSALISIGTD---LDHKVLTYGEKEIVTAATSLGALITSIFA 146

  Fly    88 GLLMDRIGRKMVLF----------FIAIPYTTFWCLIYFVQSVEFLYIGRLMAGITGGACYVVLP 142
            |...|..|||..|.          .:.:...|||.:.          :|||:.|...|...::.|
Yeast   147 GTAADIFGRKRCLMGSNLMFVIGAILQVSAHTFWQMA----------VGRLIMGFGVGIGSLIAP 201

  Fly   143 TFISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSP-PFIIGLPV----CYFICNFLI 202
            .||||||...:||||..|..|.:..|.|..|.....::|..:. ..::||.:    ..|.|...:
Yeast   202 LFISEIAPKMIRGRLTVINSLWLTGGQLVAYGCGAGLNYVNNGWRILVGLSLIPTAVQFTCLCFL 266

  Fly   203 PETPHHLVRKGKF----EAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLIKEQTEKAKSF------ 257
            |:||.:.|.||..    |..|||:        .|...|....:::.|:...|:...|:.
Yeast   267 PDTPRYYVMKGDLARATEVLKRSY--------TDTSEEIIERKVEELVTLNQSIPGKNVPEKVWN 323

  Fly   258 DYRDFITRPA-FKAYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGMCTIIIGVLQIVGN 321
            ..::..|.|: .:|......|....||:....:..:...:|.......:..:..|:.|.     |
Yeast   324 TIKELHTVPSNLRALIIGCGLQAIQQFTGWNSLMYFSGTIFETVGFKNSSAVSIIVSGT-----N 383

  Fly   322 YVTTLLC----DKYGRRILMLTS----TLGASVCLTAF---GTFTFFAEAADLSS--VDWLPLVI 373
            ::.||:.    ||.|||.::|..    |:...||..||   |.....|.|..:||  ..|..::|
Yeast   384 FIFTLVAFFSIDKIGRRTILLIGLPGMTMALVVCSIAFHFLGIKFDGAVAVVVSSGFSSWGIVII 448

  Fly   374 LSCFVFLCNIGL-VGCLFVVLVELFPAKIRSVSVSTFV-------VILSSTVFLTL--KIFPICM 428
            :...||.....| :|.:.....||||..:|.:..|...       ::::|| |||:  .|.|.
Yeast   449 VFIIVFAAFYALGIGTVPWQQSELFPQNVRGIGTSYATATNWAGSLVIAST-FLTMLQNITPA-- 510

  Fly   429 AVWGTSVTMWSCSGITFFS--FLYFCFFLEETNGKSL 463
               ||....   :|::..|  |.|||:  .|.:|..|
Yeast   511 ---GTFAFF---AGLSCLSTIFCYFCY--PELSGLEL 539

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	114/465 (25%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	105/434 (24%)
ITR1	NP_010785.1	MFS_HMIT_like	92..533	CDD:340918	118/477 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342399
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	168	1.000	Inparanoid score	I1021
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.800