DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and HXT7

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_010629.3	Gene:	HXT7 / 851943	SGDID:	S000002750	Length:	570	Species:	Saccharomyces cerevisiae

Alignment Length:	470	Identity:	108/470 - (22%)
Similarity:	187/470 - (39%)	Gaps:	96/470 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 HGLGVGWMSPVMRDLQTDESPLDFPVLVSQVSWIGSLVGIGSVMGNLIAGLLMDRIGRKMVLFFI 103
            |..|..::|.|...|                  |.|:..||..:|.:|...|.|..|||:.|..:
Yeast   103 HKDGTNYLSKVRTGL------------------IVSIFNIGCAIGGIILSKLGDMYGRKVGLIVV 149

  Fly   104 AIPYTTFWCLIYFVQSVEFLY---IGRLMAGITGGACYVVLPTFISEIADTNVRGRLGSIILLSV 165
            .:.|..  .:|..:.|:...|   |||:::|:..|...|:.|..|||::..::||.|.|...|.:
Yeast   150 VVIYII--GIIIQIASINKWYQYFIGRIISGLGVGGIAVLSPMLISEVSPKHLRGTLVSCYQLMI 212

  Fly   166 NTGVLAGYIVS--TRVDYFTSPPFIIGLPVCYFICNFLI------PETPHHLVRKGKFEAAKRSF 222
            ..|:..||..:  |: :|..|..:.:.|.:|:....|:|      ||:|.:|...||.|.||||.
Yeast   213 TAGIFLGYCTNFGTK-NYSNSVQWRVPLGLCFAWALFMIGGMTFVPESPRYLAEVGKIEEAKRSI 276

  Fly   223 MFYKNIRKNDIKAEDE--FEEMKYLLIKEQTEK-------AKSFDYR-DFITRPAFKAYASAAVL 277
            ..     .|.:..:|.  ..|::.:|...:.||       .:.|..: ..:.|....|...:...
Yeast   277 AV-----SNKVAVDDPSVLAEVEAVLAGVEAEKLAGNASWGELFSSKTKVLQRLIMGAMIQSLQQ 336

  Fly   278 LISNQFSASFCVTTY----LADVFAASHTTLNLGMCTIIIGVLQIVGNYVTTLLCDKYGRRILML 338
            |..:.:...:..|.:    |:|.|..|          |::|::.....:|...:.::||||..:|
Yeast   337 LTGDNYFFYYGTTIFKAVGLSDSFETS----------IVLGIVNFASTFVGIYVVERYGRRTCLL 391

  Fly   339 TSTLGASVCLTAF---GTFTFFAEAADLSSVDWLP--LVILSCFVFLCNIGLVGCL-FVVLVELF 397
            ......:.|:..:   |....:....|..|.....  :::.:||...|.......: :||:.|.|
Yeast   392 WGAASMTACMVVYASVGVTRLWPNGQDQPSSKGAGNCMIVFACFYIFCFATTWAPIPYVVVSETF 456

  Fly   398 PAKIRSVSVSTFVVILSSTVFLTLKIFPICMAVWGTSV---TMWSCSGITF-----------FSF 448
            |.:::|.::|    |.::..:|           ||..:   |.:....|.|           |.|
Yeast   457 PLRVKSKAMS----IATAANWL-----------WGFLIGFFTPFITGAINFYYGYVFMGCLVFMF 506

  Fly   449 LYFCFFLEETNGKSL 463
            .|....:.||.|.:|
Yeast   507 FYVLLVVPETKGLTL 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	99/437 (23%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	95/410 (23%)
HXT7	NP_010629.3	Sugar_tr	68..528	CDD:395036	108/470 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342522
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.740