DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and HXT10

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_116644.1	Gene:	HXT10 / 850536	SGDID:	S000001883	Length:	546	Species:	Saccharomyces cerevisiae

Alignment Length:	478	Identity:	121/478 - (25%)
Similarity:	206/478 - (43%)	Gaps:	70/478 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 LLLNIATFSHGLGVGWMSPVMRDLQTD------ESPLDFPVLVSQVSWIGSLVG---IGSVMGNL 85
            |::....|..|...|.:|..:.  |||      |...|....:|.|. .|.:||   ||..:|.|
Yeast    54 LMIAFGGFIFGWDTGTISGFIN--QTDFKRRFGELQRDGSFQLSDVR-TGLIVGIFNIGCALGGL 115

  Fly    86 IAGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQSVEF--LYIGRLMAGITGGACYVVLPTFISEI 148
            ..|.|.|..|||:.|..:.:.|.. ..:|....|.::  .:|||:::|:..|...|:.||.||||
Yeast   116 TLGRLGDIYGRKIGLMCVILVYVV-GIVIQIASSDKWYQYFIGRIVSGMGVGGVAVLSPTLISEI 179

  Fly   149 ADTNVRGRLGSIILLSVNTGVLAGYIVS--TRVDYFTSPPFIIGLPVCYFICNF------LIPET 205
            :..::||...|...|.:..|:..||..:  |: .|..|..:.:.|.:|:....|      ::||:
Yeast   180 SPKHLRGTCVSFYQLMITLGIFLGYCTNYGTK-KYSNSIQWRVPLGLCFAWAIFMVIGMVMVPES 243

  Fly   206 PHHLVRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLIKEQTEKA--KSFDYRDFITRPAF 268
            |.:||.|||:|.|:||......:...|.....||:.   ::...:.|:|  .:..:..|..:.|.
Yeast   244 PRYLVEKGKYEEARRSLAKSNKVTVTDPGVVFEFDT---IVANMELERAVGNASWHELFSNKGAI 305

  Fly   269 KAYASAAVLLIS-NQFSASFCVTTYLADVFAASHTTLNLGM-----CTIIIGVLQIVGNYVTTLL 327
            .......:::.| .|.:.......|...:|.|      :||     .:|::|.:.....:|...:
Yeast   306 LPRVIMGIVIQSLQQLTGCNYFFYYGTTIFNA------VGMQDSFETSIVLGAVNFASTFVALYI 364

  Fly   328 CDKYGRRILMLTSTLGASVCLTAF---GTFTFFAEAADLSSVDWL--PLVILSC-FVFLCNIGLV 386
            .||:|||..:|..:...::|...|   |....:.:..|..|....  .:::.:| |:|...|...
Yeast   365 VDKFGRRKCLLWGSASMAICFVIFATVGVTRLWPQGKDQPSSQSAGNVMIVFTCFFIFSFAITWA 429

  Fly   387 GCLFVVLVELFPAKIRSVSVSTFV--------VILSSTVFLTLKIFPICMAVWGTS---VTMWSC 440
            ...:|::.|.:|.::::.:::..|        :|...|.|:|..|        |.|   |.|
Yeast   430 PIAYVIVAETYPLRVKNRAMAIAVGANWMWGFLIGFFTPFITRSI--------GFSYGYVFM--- 483

  Fly   441 SGITFFSFLYFCFFLEETNGKSL 463
             |...||:.|..||:.||.|.:|
Yeast   484 -GCLIFSYFYVFFFVCETKGLTL 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	111/456 (24%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	103/427 (24%)
HXT10	NP_116644.1	Sugar_tr	52..512	CDD:395036	121/478 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
TreeFam	0	0.000	Not matched by this tool.
	4	3.740