DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and YFL040W

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_116613.1	Gene:	YFL040W / 850503	SGDID:	S000001854	Length:	540	Species:	Saccharomyces cerevisiae

Alignment Length:	506	Identity:	112/506 - (22%)
Similarity:	193/506 - (38%)	Gaps:	103/506 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 VTLLLNIATFSHGLGVGWMSPVMRDLQTDESPLDFPVLVSQVSWIGSLVG---IGSVMGNLIAGL 89
            :|.:|.:..|..||.|..::..:.: :|......:|..:.|    |.|:|   :|.:||..|..:
Yeast    28 ITAILTLVGFIMGLEVPSLATFLTN-KTFNEYFKYPTPLQQ----GLLMGSTPLGGIMGCFICCI 87

  Fly    90 LMDRIGRKMVLFFIAIPYTTFWCLIYFVQSVEFLYIGRLMAGITGGACYVVLPTFISEIADTNVR 154
            :.||..|........|.:.....|.:.:..:..|.|.|::.|:..|...:::.::.:|:.....|
Yeast    88 MNDRFSRIYQFQSGIIIWNIVTLLNFCIWDILGLLICRMIKGMILGNFSILVASYANEVIPRGKR 152

  Fly   155 GRLGSIILLSVNTGVLAGYIVSTRVDYFTSP-----PFIIGL--PVCYFICNFLIPETPHHLVRK 212
            |...|.|.|.:..|:|..:.:...:..:.|.     .:.||:  .:.:::.::.:||:.|.||..
Yeast   153 GSTMSYIQLCLTIGILVMHYLCIALSLWDSHFAFRIAWCIGIIPGLLFWMASYALPESYHWLVLH 217

  Fly   213 GKFEAAKRSFMFYKNIRK--NDIKAEDEFEEMKYLLIKEQTEKAKSF-------DYRDFITRPAF 268
            ||...|:.   ...|:.|  |:.:..|...||      .:.|.|..|       |:...:.|.:|
Yeast   218 GKMSEAQE---IQHNLAKKFNESQPRDAVPEM------SKIELAGDFWIGVNDLDFSKKLPRGSF 273

  Fly   269 KAYASAAVLLISNQFSASFCV---TTYLADV---------FAAS-----HTTLNLGMCTII---- 312
            |.......|.:..|||....:   .||:.::         |.:|     :..|:|...|.|
Yeast   274 KPLILGMTLQLLVQFSGINIILGYITYICEIVGLEGNVKLFTSSIPYFINMVLSLLPITFIDYTS 338

  Fly   313 ------IGVLQIVGNYVTT-LLCDKYGRRI------LMLTSTLG---------ASVCLTAFGTFT 355
                  :|...|.|..:|. .|..|||:..      ..|..::|         .::|....|.|
Yeast   339 RKLITLLGGFPISGLLITIGALFVKYGQDTKPIDGNRSLVWSIGENPFVGGWILTLCFLIVGIF- 402

  Fly   356 FFAEAADLSSVDW------LP-LVILSCFVFLCNIGLVGCLFVVLVELFPAKIRSVSVSTFVVIL 413
                |..|||:.|      || .|.:..|......|.:|..  :|..|.|..|..:..:||::..
Yeast   403 ----AMSLSSIPWVYTNEMLPSRVKVKGFAICVTFGWLGNF--ILTFLCPVMIERLKGTTFIIFG 461

  Fly   414 SSTVFLTLKIFPICMAVWGTSVTMWSCSGI-TFFSFLYFCFFLEETNGKSL 463
            |.|..::|.:.     :|.......|...| .||.|       |...|.:|
Yeast   462 SLTFLISLSVL-----IWFPETKGMSIEDIDKFFEF-------ESKEGTNL 500

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	105/482 (22%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	101/455 (22%)
YFL040W	NP_116613.1	MFS_HXT	28..490	CDD:340914	106/487 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900