Protein Alignment CG3285 and SLC2A1

DIOPT Version :9

• Sequence 1: NP_001285583.1
• Gene: CG3285 / 33547
• FlyBaseID: FBgn0031522
• Length: 466
• Species: Drosophila melanogaster
• Sequence 2: NP_006507.2
• Gene: SLC2A1 / 6513
• HGNCID: 11005
• Length: 492
• Species: Homo sapiens
• Alignment Length: 436
• Identity: 100/436 - (22%)
• Similarity: 167/436 - (38%)
• Gaps: 93/436 - (21%)

  Fly    74 SLVGIGSVMGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQSV-----------EFLYIGR 127
            ::..:|.::|:...||.::|.||:..:..:.        |:.||.:|           |.|.:||
Human    70 AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMN--------LLAFVSAVLMGFSKLGKSFEMLILGR 126

  Fly   128 LMAGITGGACYVVLPTFISEIADTNVRGRLGSIILLSVNTGVLAGYI-----VSTRVDYF---TS 184
            .:.|:..|.....:|.::.|::.|.:||.||::..|.:..|:|...:     :....|.:   .|
Human   127 FIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLS 191

  Fly   185 PPFI------IGLPVCYFICNFLIPETPHHLVRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMK 243
            ..||      |.||.|        ||:|..|:.....|...:|.:  |.:| .......:.:|||
Human   192 IIFIPALLQCIVLPFC--------PESPRFLLINRNEENRAKSVL--KKLR-GTADVTHDLQEMK 245

  Fly   244 YLLIKEQTEKAKSFDYRDFITRPAFK-AYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLG 307
            .  ...|..:.|.....:....||:: ....|.||.:|.|.|....|..|...:|..:.....:
Human   246 E--ESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPV- 307

  Fly   308 MCTIIIGVLQIVGNYVTTLLCDKYGRRILMLTSTLGASVCLTAFGTFTFFAEAADLSSVDW---L 369
            ..||..|::......|:..:.::.|||.|.|....|.:.|     ........|.|..:.|   |
Human   308 YATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGC-----AILMTIALALLEQLPWMSYL 367

  Fly   370 PLVILSCFVFLCNIGLVGCLFVVLVELF-----PAKIR----SVSVSTFVV---------ILSST 416
            .:|.:..||....:|.....:.::.|||     ||.|.    |...|.|:|         :....
Human   368 SIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPY 432

  Fly   417 VFLTLKIFPICMAVWGTSVTMWSCSGITFFSFLYFCFFLEETNGKS 462
            ||:   ||.:.:              :.||.|.|  |.:.||.|::
Human   433 VFI---IFTVLL--------------VLFFIFTY--FKVPETKGRT 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	92/415 (22%)
		MFS_1	32..419	CDD:284993	89/391 (23%)
SLC2A1	NP_006507.2	MFS_GLUT_Class1	14..458	CDD:340989	99/433 (23%)
		Monosaccharide binding. /evidence=ECO:0000269|PubMed:24847886	282..288		2/5 (40%)
		Disordered. /evidence=ECO:0000305|PubMed:30197081	468..492

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144101
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840