Protein Alignment CG3285 and Slc2a8

DIOPT Version :9

• Sequence 1: NP_001285583.1
• Gene: CG3285 / 33547
• FlyBaseID: FBgn0031522
• Length: 466
• Species: Drosophila melanogaster
• Sequence 2: NP_062361.1
• Gene: Slc2a8 / 56017
• MGIID: 1860103
• Length: 477
• Species: Mus musculus
• Alignment Length: 481
• Identity: 122/481 - (25%)
• Similarity: 214/481 - (44%)
• Gaps: 72/481 - (14%)

  Fly    19 GRRIRHQFLVTLLLNIATFSHGLGVGWMSPVMRDLQTDESPL----DFPVLVSQVSWIGSLVGIG 79
            |||:   ||.:....:...|.|..:|:.||.:..|:....|.    |     :..||.|::|.:|
Mouse    23 GRRV---FLASFAAALGPLSFGFALGYSSPAIPSLRRTAPPALRLGD-----NAASWFGAVVTLG 79

  Fly    80 SVMGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQSVEFLYIGRLMAGITGGACYVVLPTF 144
            :..|.::.|.|:||.|||:.|....:|:.|.:.:|...:.|..|..|||:.|:..|...:|.|.:
Mouse    80 AAAGGILGGWLLDRAGRKLSLLLCTVPFVTGFAVITAARDVWMLLGGRLLTGLACGVASLVAPVY 144

  Fly   145 ISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDY------FTSPPFIIGLPVCYFICNFLIP 203
            |||||...|||.|||.:.|.|.||:|..|:....:::      ...||.::.|.:||      :|
Mouse   145 ISEIAYPAVRGLLGSCVQLMVVTGILLAYVAGWVLEWRWLAVLGCVPPTLMLLLMCY------MP 203

  Fly   204 ETPHHLVRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLIKEQTEKAKSFDYRDF----IT 264
            |||..|:.:.:::.|..:..|...       :|:.:|           |.....:::.|    :.
Mouse   204 ETPRFLLTQHQYQEAMAALRFLWG-------SEEGWE-----------EPPVGAEHQGFQLALLR 250

  Fly   265 RPA-FKAYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGMCTIIIGVLQIVGNYVTTLLC 328
            ||. :|.......|::..|.|....:..|...:|..:... :..:.::.:|::|::...|..|:.
Mouse   251 RPGIYKPLIIGISLMVFQQLSGVNAIMFYANSIFEEAKFK-DSSLASVTVGIIQVLFTAVAALIM 314

  Fly   329 DKYGRRILMLTSTLGASVCLTAFGTFTFFAEA--ADLSSVDWLPLVILSCFVFLCNIGL----VG 387
            |:.|||:|:..|.:.....::||||:....::  ::.|.|..:|:......|   .:||    ||
Mouse   315 DRAGRRLLLALSGVIMVFSMSAFGTYFKLTQSLPSNSSHVGLVPIAAEPVDV---QVGLAWLAVG 376

  Fly   388 --CLFV-------------VLVELFPAKIRSVSVSTFVVILSSTVFLTLKIFPICMAVWGTSVTM 437
              |||:             ::.|:||..::.|:....|:......||..|.|...|.:.......
Mouse   377 SMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWFMAFLVTKEFSSVMEMLRPYGAF 441

  Fly   438 WSCSGITFFSFLYFCFFLEETNGKSL 463
            |..:.....|.|:....:.||.|::|
Mouse   442 WLTAAFCALSVLFTLTVVPETKGRTL 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	111/449 (25%)
		MFS_1	32..419	CDD:284993	105/422 (25%)
Slc2a8	NP_062361.1	Dileucine internalization motif. /evidence=ECO:0000269|PubMed:16723738	12..13
		Sugar_tr	29..474	CDD:278511	117/472 (25%)
		MFS	31..459	CDD:119392	113/460 (25%)
		Monosaccharide binding. /evidence=ECO:0000250|UniProtKB:P11166	268..274		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834248
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.840