DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3285 and CG31100

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001262395.1	Gene:	CG31100 / 41075	FlyBaseID:	FBgn0051100	Length:	716	Species:	Drosophila melanogaster

Alignment Length:	606	Identity:	126/606 - (20%)
Similarity:	223/606 - (36%)	Gaps:	186/606 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 RRIRHQFLVTLLLNIATFSHGLGVGWMSPVMRDLQTDE--SPLDFPVLVS--QVSWIGSLVGIGS 80
            ||...|||...:.||..|.:|:.:|:.:.|:..:|..|  |.....:|::  ::||..|:..|..
  Fly    45 RRALPQFLAVSIKNILLFGYGMTLGFPTIVIPAIQGGEGRSETSGDILLNKDEISWFSSINLICV 109

  Fly    81 VMGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQSVEFLYIGRLMAGITGGACYVVLPTFI 145
            .:|.|.:|||...:|::..:.|:.:|....|.:.:|....|.||....:||:.||.....:.|::
  Fly   110 PLGCLFSGLLTQPLGKRRAMQFVNLPILAAWLMFHFATRTEHLYAALCLAGLGGGLMEAPVLTYV 174

  Fly   146 SEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSPPFIIGLPVCYFICNFLIPETPHHLV 210
            :||.:...||.|.::....|.|||...:|:.:.:|:.:........||...|....:||:|..|:
  Fly   175 AEITEPKYRGILSALGTTCVITGVFIQFILGSLMDWRSVAAVSSAFPVITIIMLCFVPESPVWLI 239

  Fly   211 RKGKFEAAKRSFMFYKN-IRKNDIKAEDEFEEMKYLLIKEQTEKAKSFDYRDFITRPAFKAYAS- 273
            |:.:|..|.:|..:.:. :.::.|:|  ||.::                |.:.||:.|.:..|.
  Fly   240 REQRFREAVKSLQWLRGWVPEHMIEA--EFNQL----------------YDELITQKAIELSADG 286

  Fly   274 -----------------------AAVLLIS-----NQFSASFCVTTYLADVFAASHTTLNLGMCT 310
                                   ...||:|     ..||....:.||...:|......:|....|
  Fly   287 IPPPGQRRTLGQRLRMWRKRSFLVPFLLVSFSFFTGHFSGKTPLQTYAVQIFHTLKAPMNKYHAT 351

  Fly   311 IIIGVLQIVGNYVTTLLCDKYGRRILMLTSTLGASVCLTAFGTFT---FFAE------------- 359
            |::||.:::...:..:|....|:|.|:|.||:|..:|.  |||.|   |.:|
  Fly   352 ILLGVAEMLATILGVVLIHFTGKRPLVLVSTVGTGLCF--FGTATYAHFLSEVPGFTVNNVVVNA 414

  Fly   360 ---------------------------------------------------------AADLSSVD 367
                                                                     ..::.:.|
  Fly   415 SSIMPKEGILSQQNISKIFETEQQAIRQETERFTTQLPDIETTTLFDQEIYNRSRRDVVEMMTTD 479

  Fly   368 ---------------------------------------------------WLPLVILSCFVFLC 381
                                                               |:||::|....|..
  Fly   480 APMDTTMWPEPSSSPEPIASSSLAPPSTSVKPPLVEELLLVVPKQEHNYLVWVPLILLLLSAFFS 544

  Fly   382 NIGLVGCLFVVLVELFPAKIRSVSVSTFV----VILSSTVFLTLKIFPICMAVWGTSVTMWSCSG 442
            ::|:....::::.|:|||:||: |.|.|.    .|..   ||..|:|.:.::......|....:.
  Fly   545 HLGIRMLPWILIGEVFPAEIRN-SASGFAGGVGYIFG---FLANKLFLLMLSALTLPGTFAFYAS 605

  Fly   443 ITFFSFLYFCFFLEETNGKSL 463
            :.||..:...|.|.||.|::|
  Fly   606 VAFFGTVVLYFTLPETEGRTL 626

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	113/575 (20%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	108/548 (20%)
CG31100	NP_001262395.1	MFS	59..>232	CDD:119392	45/172 (26%)
		Sugar_tr	98..633	CDD:278511	111/553 (20%)
		MFS	<531..616	CDD:119392	23/88 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920