DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3285 and CG1213

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_001246937.1	Gene:	CG1213 / 40728	FlyBaseID:	FBgn0037387	Length:	491	Species:	Drosophila melanogaster

Alignment Length:	473	Identity:	138/473 - (29%)
Similarity:	236/473 - (49%)	Gaps:	25/473 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 TFKLRLASV-FANPNCLLGRRIRHQFLVTLLLNIATFSHGLGVGWMSPV---MRDLQTDESPLDF 62
            ||::|..:. ..:|..:...||   |:..:..|::.|..|..:||.||:   ::...|.:|||..
  Fly    21 TFQIREGNTRTMSPEPVKSGRI---FMAAVAANLSAFVVGTTLGWTSPIGPKLKSEDTSDSPLSR 82

  Fly    63 PVLVSQVSWIGSLVGIGSVMGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQSVEFLYIGR 127
            |:...:.:||.||:.:|:::...:||.:.||||||.||...::.:...:.|......|..||:.|
  Fly    83 PITSDEDAWISSLIAVGALVAPFVAGPMADRIGRKWVLLSSSLFFVLAFGLNMVASEVWILYMSR 147

  Fly   128 LMAGITGGACYVVLPTFISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSPPFIIGLP 192
            |:.|...|....|.|.::.||:..||||..||::.|.:..|:|..|.:...|.|.......|.:|
  Fly   148 LIQGFGVGFVMTVQPMYVGEISTDNVRGATGSLMQLFIVGGILYVYAIGPYVSYQALQWCCIVVP 212

  Fly   193 VCYFICNFLIPETPHHLVRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLIKEQTEKAKSF 257
            |.:.:..:::||:|:....||:...|.:|..|.:......:  .||..|::..:.:....|....
  Fly   213 VVFDLVFYMMPESPYFFAGKGRKSEALKSLQFLRGQSAEGV--HDEMAEIQANVEEAMASKGTVM 275

  Fly   258 D-YRDFITRPAFKAYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGMCTIIIGVLQIVGN 321
            | :::...|   :|....|.|:...|.|....|......:||:::|.|:..:.|||||.:|:..:
  Fly   276 DLFKNAGNR---RALFICAGLISFQQLSGINVVLFNSQSIFASANTGLDPAIATIIIGCVQVGSS 337

  Fly   322 YVTTLLCDKYGRRILMLTSTLGASVCLTAFGTFTFFAE--AADLSSVDWLPLVILSCFVFLCNIG 384
            .:|.|:.|:.||::::|||:...|:.|.|.|.| |:.:  ..|:|||.|:|:..|..:..:...|
  Fly   338 ALTPLVADRLGRKVMLLTSSSVMSIGLAALGAF-FYMQLVKGDISSVVWMPVPALIIYNIVYCTG 401

  Fly   385 LVGCLFVVLVELFPAKIRSVSVSTFVVILSSTV----FLTLKIFPICMAVWGTSVTMWSCSGITF 445
            .....:.||.|:|||.|:||:.|    :::||.    ||....:|...|: |:....|..:....
  Fly   402 FGPLPWAVLGEMFPANIKSVASS----VVASTCWTLGFLVTFFYPSLDAL-GSYYAFWLFAVCMV 461

  Fly   446 FSFLYFCFFLEETNGKSL 463
            .:|.:..|.:.||.|.||
  Fly   462 VAFFFVLFVVMETKGLSL 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	124/423 (29%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	118/396 (30%)
CG1213	NP_001246937.1	SP	42..482	CDD:273317	133/452 (29%)
CG1213	NP_001246937.1	MFS	47..460	CDD:119392	124/423 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48021
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
	5	4.920