DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and Slc2a12

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_849265.2	Gene:	Slc2a12 / 353169	MGIID:	3052471	Length:	622	Species:	Mus musculus

Alignment Length:	574	Identity:	133/574 - (23%)
Similarity:	218/574 - (37%)	Gaps:	157/574 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 ASVFANPNCLLGRRIRHQFLVTLLLNIATFSHGLGVGWMSPVMRDLQTDESPLDFPVLV----SQ 68
            ||...:|.|..|..: ..||.::...|:....|..:|.:|..:..::|        :|.    .|
Mouse    28 ASGGGHPACAGGPSM-FTFLTSVTAAISGLLVGYELGLISGALLQIRT--------LLALTCHEQ 83

  Fly    69 VSWIGSLVGIGSVMGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCL-----IYFVQSVEF--LYIG 126
            ...:.||: ||:.:.:|..|:|:||.||::.:...:       ||     :..:.|:.:  |.:|
Mouse    84 EMVVSSLL-IGAFLASLTGGVLIDRYGRRLAIILSS-------CLLGLGSLVLIMSLSYTLLIMG 140

  Fly   127 RLMAGITGGACYVVLPTFISEIADTNVRGRLGSIILLSVNTGVLAGYI-------VSTRVDYFTS 184
            |:..|::.....:....:|:|||..:.||.|.|:..|.:.||:|..||       :|....|...
Mouse   141 RVAIGVSISLSSIATCVYIAEIAPQHRRGLLVSLNELMIVTGILFAYISNYAFANISNGWKYMFG 205

  Fly   185 PPFIIGLPVCYFICNFLIPETPHHLVRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLIKE 249
              .:|.|.|...|..:.:|.:|..||.||:.|:|.      |.:||..: ..|..||:  .|||.
Mouse   206 --LVIPLGVLQAIAMYFLPPSPRFLVMKGQEESAG------KVLRKLRV-ISDTTEEL--TLIKS 259

  Fly   250 QTEKAKSFDYRD-FITRPAFKAYASAAVLLI-----SNQFSASFCVTTYLADVFAASHTTLNLGM 308
            ..:....:.:.| |.::...:......:.|:     :.|.:..|..:|.|..|...|:...:|
Mouse   260 SLKDEYQYSFWDLFRSKDNMRTRILIGLTLVFFVQTTGQPNILFYASTVLKSVGFQSNEAASL-- 322

  Fly   309 CTIIIGVLQIVGNYVTTLLCDKYGRRILML--TSTLGAS-----------------VC------- 347
            .:..:||:::|.....|||.|..|.:..:.  :|.:.||                 :|
Mouse   323 ASTGVGVVKVVSTIPATLLVDHIGSKTFLCIGSSVMSASLLTMGIVNLNINMNFTNICRSHSLLN 387

  Fly   348 ---------------------------LTAFG-----------------TFTFFAEAADLSSVD- 367
                                       :|.:.                 |||.....|.||..:
Mouse   388 QSLEEFVFYATGNLSISNSSLREHFKRITPYSKGSFMPMGNGMEPKGEMTFTSSLPNAGLSRTEH 452

  Fly   368 --------------WLPLVILSCFVFLCNIGLVGCLFVVLVELFPAKIR------SVSVSTFVVI 412
                          ||.|..|..:|...:|||....::||.|:||..||      :.|::..|.:
Mouse   453 QGVTDTAVVPAAYKWLSLASLLVYVAAFSIGLGPMPWLVLSEIFPGGIRGRAMALTSSMNWGVNL 517

  Fly   413 LSSTVFLTLKIFPICMAVWGTSVTMWSCSGITFFSFLYFCF---FLEETNGKSL 463
            |.|..|||:      ..:.|.|   |.|...|..|.....|   |:.||.|.||
Mouse   518 LISLTFLTV------TDLIGLS---WVCFIYTIMSLASLAFVVLFIPETKGCSL 562

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	117/528 (22%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	110/501 (22%)
Slc2a12	NP_849265.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..26
		Sugar_tr	48..569	CDD:278511	126/553 (23%)
		MFS	49..>367	CDD:119392	83/346 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834326
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53651
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.850