DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_006237357.1	Gene:	Slc2a3 / 25551	RGDID:	3706	Length:	495	Species:	Rattus norvegicus

Alignment Length:	496	Identity:	119/496 - (23%)
Similarity:	203/496 - (40%)	Gaps:	109/496 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FLVTLLLNIATFSHGLGVGWMS---PVMRDL---QTDESPLDFP---VLVSQVSWIGSLVGIGSV 81
            |.|| :..|.:|..|...|.::   .:::|.   ..:|...|.|   :|.:..|...::..:|.:
  Rat    14 FAVT-VATIGSFQFGYNTGVINAPETIIKDFLNYTLEERLEDLPSEGLLTTLWSLCVAIFSVGGM 77

  Fly    82 MGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYF---VQSVEFLYIGRLMAGITGGACYVVLPT 143
            :|:...||.::|.||:..:..:.:......||:.|   .:|||.|.:|||:.||..|.|...:|.
  Rat    78 IGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLIIGIFCGLCTGFVPM 142

  Fly   144 FISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSP----PFIIG------------LP 192
            :|.|::.|.:||..|::..|.:..|:|...:..  :|:....    |.::|            ||
  Rat   143 YIGEVSPTALRGAFGTLNQLGIVVGILVAQVFG--LDFILGSEELWPGLLGLTIIPAILQSAALP 205

  Fly   193 VCYFICNFLIPETPHHLVRKGKFEAAKRSFMFYKNIRKNDIKAED-------------EFEEMKY 244
            .|        ||:|..|:..                ||.:.:|.:             |.:|||.
  Rat   206 FC--------PESPRFLLIN----------------RKEEDQATEILQRLWGTPDVIQEIQEMKD 246

  Fly   245 LLIKEQTEKA-------KSFDYRDFITRPAFKAYASAAVLLISNQFSASFCVTTYLADVFAASHT 302
            ..|:...||.       ||..|        |:....:.||.:|.|||....|..|...:|.
  Rat   247 ESIRMSQEKQVTVLELFKSPSY--------FQPLLISVVLQLSQQFSGINAVFYYSTGIFQ---- 299

  Fly   303 TLNLGM-----CTIIIGVLQIVGNYVTTLLCDKYGRRILMLTSTLGASVCLTAFGTFTFFAEAAD 362
              :.|:     .||..||:..:...|:..|.::.|||.|.:....|.:|| :.|.|.:...: .:
  Rat   300 --DAGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVC-SVFMTISLLLK-DE 360

  Fly   363 LSSVDWLPLVILSCFVFLCNIGLVGCLFVVLVELF-----PAKIRSVSVSTFVVILSSTVFLTLK 422
            ..::.::.:|.:..:|....||.....:.::.|||     ||.:.....|.:     ::.||...
  Rat   361 YEAMSFVCIVAILVYVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNW-----TSNFLVGM 420

  Fly   423 IFPICMAVWGTSVTMWSCSGITFFSFLYFCFF-LEETNGKS 462
            .||...|..|..|.:...:.:.|  ||.|.|| :.||.|::
  Rat   421 FFPSAAAYLGAYVFIIFAAFLVF--FLIFTFFKVPETKGRT 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	108/471 (23%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	100/444 (23%)
Slc2a3	XP_006237357.1	Sugar_tr	15..467	CDD:278511	118/495 (24%)
Slc2a3	XP_006237357.1	MFS	16..450	CDD:119392	113/483 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337743
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840