DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and Slc2a1

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_620182.1	Gene:	Slc2a1 / 24778	RGDID:	3704	Length:	492	Species:	Rattus norvegicus

Alignment Length:	431	Identity:	98/431 - (22%)
Similarity:	168/431 - (38%)	Gaps:	83/431 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    74 SLVGIGSVMGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYFVQSV-----------EFLYIGR 127
            ::..:|.::|:...||.::|.||:..:..:.        |:.||.:|           |.|.:||
  Rat    70 AIFSVGGMIGSFSVGLFVNRFGRRNSMLMMN--------LLAFVSAVLMGFSKLGKSFEMLILGR 126

  Fly   128 LMAGITGGACYVVLPTFISEIADTNVRGRLGSIILLSVNTGVLAGYI-----VSTRVDYF---TS 184
            .:.|:..|.....:|.::.|::.|.:||.||::..|.:..|:|...:     :....|.:   .|
  Rat   127 FIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIMGNADLWPLLLS 191

  Fly   185 PPFIIGLPVCYFI--CNFLIPETPHHLVRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLI 247
            ..||..|..|..:  |    ||:|..|:.....|...:|.:  |.:|.......| .:|||
  Rat   192 VIFIPALLQCILLPFC----PESPRFLLINRNEENRAKSVL--KKLRGTADVTRD-LQEMK---- 245

  Fly   248 KE--QTEKAKSFDYRDFITRPAFK-AYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGMC 309
            :|  |..:.|.....:....||:: ....|.||.:|.|.|....|..|...:|..:.....: ..
  Rat   246 EEGRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEKAGVQQPV-YA 309

  Fly   310 TIIIGVLQIVGNYVTTLLCDKYGRRILMLTSTLGASVCLTAFGTFTFFAEAADLSSVDWLPLVIL 374
            ||..|::......|:..:.::.|||.|.|....|.:.|...........|  .|..:.:|.:|.:
  Rat   310 TIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAVLMTIALALLE--QLPWMSYLSIVAI 372

  Fly   375 SCFVFLCNIGLVGCLFVVLVELFPAKIRSVSV---------STFVV---------ILSSTVFLTL 421
            ..||....:|.....:.::.|||....|..:|         |.|:|         :....||:
  Rat   373 FGFVAFFEVGPGPIPWFIVAELFSQGPRPAAVAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFI-- 435

  Fly   422 KIFPICMAVWGTSVTMWSCSGITFFSFLYFCFFLEETNGKS 462
             ||.:.:              :.||.|.|  |.:.||.|::
  Rat   436 -IFTVLL--------------VLFFIFTY--FKVPETKGRT 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	90/410 (22%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	87/386 (23%)
Slc2a1	NP_620182.1	MFS_GLUT_Class1	14..458	CDD:340989	97/428 (23%)
		Monosaccharide binding. /evidence=ECO:0000250\|UniProtKB:P11166	282..288		2/5 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	468..492
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337860
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840