DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and Slc2a3

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	XP_006505885.1	Gene:	Slc2a3 / 20527	MGIID:	95757	Length:	495	Species:	Mus musculus

Alignment Length:	472	Identity:	114/472 - (24%)
Similarity:	204/472 - (43%)	Gaps:	61/472 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 FLVTLLLNIATFSHGLGVGWMS---PVMRDL---QTDESPLDFP---VLVSQVSWIGSLVGIGSV 81
            |.|| :..|.:|..|...|.::   .:::|.   ..:|...|.|   :|.:..|...::..:|.:
Mouse    14 FAVT-VATIGSFQFGYNTGVINAPETILKDFLNYTLEERLEDLPSEGLLTALWSLCVAIFSVGGM 77

  Fly    82 MGNLIAGLLMDRIGRKMVLFFIAIPYTTFWCLIYF---VQSVEFLYIGRLMAGITGGACYVVLPT 143
            :|:...||.::|.||:..:..:.:......||:.|   .:|||.|.:|||:.||..|.|...:|.
Mouse    78 IGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGLCTGFVPM 142

  Fly   144 FISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSP----PFIIG------------LP 192
            :|.|::.|.:||..|::..|.:..|:|...|..  :|:....    |.::|            ||
Mouse   143 YIGEVSPTALRGAFGTLNQLGIVVGILVAQIFG--LDFILGSEELWPGLLGLTIIPAILQSAALP 205

  Fly   193 VCYFICNFLIPETPHHLVRKGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLIKEQTEKAKSF 257
            .|        ||:|..|:...| |..:.:.:..:....:|:  ..|.:|||...::...|  |..
Mouse   206 FC--------PESPRFLLINKK-EEDQATEILQRLWGTSDV--VQEIQEMKDESVRMSQE--KQV 257

  Fly   258 DYRDFITRPAF-KAYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGM-----CTIIIGVL 316
            ...:....|.: :....:.||.:|.|.|....|..|...:|.      :.|:     .||..||:
Mouse   258 TVLELFRSPNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFK------DAGVQEPIYATIGAGVV 316

  Fly   317 QIVGNYVTTLLCDKYGRRILMLTSTLGASVCLTAFGTFTFFAEAADLSSVDWLPLVILSCFVFLC 381
            ..:...|:..|.::.|||.|.:....|.:|| :.|.|.:...: .|..::.::.:|.:..:|...
Mouse   317 NTIFTVVSLFLVERAGRRTLHMIGLGGMAVC-SVFMTISLLLK-DDYEAMSFVCIVAILIYVAFF 379

  Fly   382 NIGLVGCLFVVLVELFPAKIRSVSVSTFVVILSSTVFLTLKIFPICMAVWGTSVTMWSCSGITFF 446
            .||.....:.::.|||....|..:::.......::.||...:||...|..|..|.:...:.:.|
Mouse   380 EIGPGPIPWFIVAELFSQGPRPAAIAVAGCCNWTSNFLVGMLFPSAAAYLGAYVFIIFAAFLIF- 443

  Fly   447 SFLYFCFF-LEETNGKS 462
             ||.|.|| :.||.|::
Mouse   444 -FLIFTFFKVPETKGRT 459

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	103/447 (23%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	95/420 (23%)
Slc2a3	XP_006505885.1	MFS_GLUT_Class1	14..458	CDD:340989	113/469 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834192
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840