DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and Y37A1A.3

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_502675.4	Gene:	Y37A1A.3 / 189599	WormBaseID:	WBGene00012536	Length:	500	Species:	Caenorhabditis elegans

Alignment Length:	495	Identity:	109/495 - (22%)
Similarity:	184/495 - (37%)	Gaps:	113/495 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LNIATFSHGLGVGWMSPVMRDLQTDESPLDFPVLVSQVSWIGSLVGIGSVMGNLIAGLLMDRIGR 96
            |.|...:.|..:.:::........|::.|..  |.::.|:|.::..:||..|..:...:.:|.||
Worm    43 LLITNPAQGAFIKFLNASKHSNNPDDNELSH--LENEWSFIVAIFFLGSATGAFLIKTVAERFGR 105

  Fly    97 K---MVLFFIAI-----PYTTFWCLIYFVQSVEFLYIGRLM-AGITGGACYVVLPTFISEIADTN 152
            |   :|..|..:     ...:||    .|..:.|::...|| .|||  ....:...|::|.:...
Worm   106 KKGVIVSLFAQVTSSMLTIVSFW----IVNHILFIFARFLMGVGIT--ISMGIAAMFVTESSPAY 164

  Fly   153 VRGRL----GSIILLSVNTGV------------------LAGYIVSTRVDYFTSPPFIIGLPVCY 195
            .||..    |.::.||:..|.                  |...|::|.|        ::.||..:
Worm   165 CRGVSSLINGVLLQLSITVGAVMAMPNVLGNETHWWYLYLFQLIINTTV--------LVILPWVH 221

  Fly   196 FICNFLI-PETPHHLVR---KGKFEAAKRSFMFYKNIRKNDIKAEDEFEEMKYLLIKEQTEKAKS 256
            ...::|. .:..||.:.   |.|..|   |..||..|      ::.|.|.....|| |..:..:|
Worm   222 ESPSYLASQDIKHHELHAMFKAKIVA---SVKFYHGI------SDPEAEVFADNLI-ETHQITRS 276

  Fly   257 FDYRDFITRPAFKAYASAAVLLISNQFSASFCVTTYLADVFAASHTTLNLGM-------CTIIIG 314
            .:....:.:..|....:...::::  ||.:....|.: :.| |....:|:||       ....|.
Worm   277 QESIISVWKSPFNRRGTLLGMMVT--FSMAMSGITVI-NAF-AFEILMNVGMKQDTAAIANAAIC 337

  Fly   315 VLQIVGNYVTTLLCDKYGRRILMLTSTLG--ASVCLTAFGTFTFFAEAADLSSVDWLPLVILSCF 377
            .....|..|:|.:.|.:|||.|:: ||.|  |.|.:...|....|||..: ..|.:..:..:..|
Worm   338 FFSFAGILVSTKIIDHFGRRPLLI-STFGCLAVVNVVIVGLMYTFAETQN-QIVSYFLISAICMF 400

  Fly   378 VFLCNIGLVGCLFVVLVELFPAKIRSVS------VSTFVVILSSTVFLTLK-------------I 423
            .||..:|.......:..||.|...||.|      |...|..|..|.:|.:|             :
Worm   401 NFLFAMGPGPLSMFITGELVPQNCRSASSVWTNAVMAVVRFLILTFYLPVKNMTSEFMAYAIFFV 465

  Fly   424 FPICMAVWGTSVTMWSCSGITFFSFLYFCFFLEETNGKSL 463
            .|:.:||                  |...|.|.||.|:::
Worm   466 VPMIVAV------------------LVIFFLLPETKGRNV 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	103/473 (22%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	98/436 (22%)
Y37A1A.3	NP_502675.4	MFS_GLUT_Class1_2_like	28..485	CDD:340915	108/491 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157974
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X26
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.850