DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3285 and F14E5.1

DIOPT Version :9

Sequence 1:	NP_001285583.1	Gene:	CG3285 / 33547	FlyBaseID:	FBgn0031522	Length:	466	Species:	Drosophila melanogaster
Sequence 2:	NP_495772.2	Gene:	F14E5.1 / 184470	WormBaseID:	WBGene00008799	Length:	472	Species:	Caenorhabditis elegans

Alignment Length:	504	Identity:	117/504 - (23%)
Similarity:	195/504 - (38%)	Gaps:	111/504 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 IRHQFLVTLLLNIATFSHGLGVGWMSPVMRDLQT-------------DESPLDFPVLVSQVSWIG 73
            ::...:..|:...:.|::|....:::..:.:.:|             .|...|....|....|.
Worm     8 VKQVCIFALIAFASNFNYGFSTTYINTSVDEFKTFLNTSLSRRHVIMTEEKYDLIWNVFLNCWF- 71

  Fly    74 SLVGIGSVMGNLIAGLLMDRIGRKMVLFF---IAIPYTTFWCLIYFVQSVEFLYIGRLMAGITGG 135
                |||..|..|..:..:|.||::....   :|...:...||.......|.|.:.|.:..|...
Worm    72 ----IGSFFGVWINSIFSERFGRRVGFLIGNSVAFISSILQCLSLIWYCPELLIVSRFITSICMA 132

  Fly   136 ACYVVLPTFISEIADTNVRGRLGSIILLSVNTGVLAGYIVSTRVDYFTSPPFIIG---------- 190
            |.|.....|:.|.:.|::||....:..:|        |...|.|..|....:|||
Worm   133 ATYQSCILFLQECSPTHLRGSFSFLSEVS--------YSSMTMVGSFLGQDYIIGSHLFWLCFFV 189

  Fly   191 LPVCYF--ICNFLIPETPHH-LVRKGKFEAAKRSFMFY-----------KNIRK-----NDIKAE 236
            :|.|.|  :..|::||||.. |:.|.:.|.|.:|..:|           ::|||     .|....
Worm   190 VPFCLFFTLILFILPETPKFLLISKDEEEEAIKSVKYYHGDGTDAKQVLEDIRKEAECEQDSSKS 254

  Fly   237 DEFEEMKYLLIKEQTEKAKSFDYRDFITRPAFKAYASA--------AVLLISNQFSASFCVTTYL 293
            ..|::||.|.    ||:.         .|.|.....||        |:||.|..|..:..|.:.:
Worm   255 TTFQKMKELF----TERH---------LRMALILSVSALTNTVGLWALLLSSTFFLENANVESEI 306

  Fly   294 ADVFAASHTTLNLGMCTIIIGVLQIVGNYVTTLLCDKYGRRILMLTSTLGASVCLTAFGTFTFFA 358
            |:            ..|..:|:..:.|.....::.:|.|||.|:|..|...::.|.|   |.|||
Worm   307 AE------------WSTTAMGLAYVSGTITGGIVIEKVGRRKLLLLFTFLNNLALIA---FVFFA 356

  Fly   359 EAADLSSVDWLP---LVILSCFVFLCNIGLVGCLFVVLVELFPAKIRSV------SVSTFVVILS 414
            :...|  :|.:.   ||.|..:.:....|:....:.:..||.|.|.||:      |::|.:|::|
Worm   357 KIRIL--IDPMKYGCLVALIIYGYTYGTGVGPISWFISSELVPQKHRSIAQSVAYSMNTVMVVIS 419

  Fly   415 STVFLTLKIFPICMAVWGTSVTMWSCSGITFFSFLYFCFFLEETNGKSL 463
                 |..:.|: .:|.|:...:...|..:|.|.|....:|.||.|:.:
Worm   420 -----TFTVLPL-YSVIGSYAFLILYSIPSFISMLILFRYLPETKGREI 462

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3285	NP_001285583.1	MFS	29..443	CDD:119392	110/475 (23%)
CG3285	NP_001285583.1	MFS_1	32..419	CDD:284993	104/448 (23%)
F14E5.1	NP_495772.2	MFS_GLUT_Class1_2_like	14..460	CDD:340915	116/494 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D430696at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920