DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and SIT1

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_010849.3	Gene:	SIT1 / 856644	SGDID:	S000000791	Length:	628	Species:	Saccharomyces cerevisiae

Alignment Length:	243	Identity:	48/243 - (19%)
Similarity:	94/243 - (38%)	Gaps:	66/243 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   227 PEYLSELN------EFHAELRSRDKNVGSTPMSHGYIIRLTFVSFLLTVCAKLSGVFVELNYAAD 285
            |.|:..::      |.:||:.:|       |:   |.:.|.|..||:.....|.|   .:.|...
Yeast    44 PSYIELIDPGVHNIEIYAEMYNR-------PI---YRVALFFSLFLIAYAYGLDG---NIRYTFQ 95

  Fly   286 FLGRTGYSTETNYVVLASAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVIALA-LFKAYGHLW 349
            ....:.||   .:.:|::..|...::| .||    :.....||.:|...:::.:: :|.:.|.:
Yeast    96 AYATSSYS---QHSLLSTVNCIKTVIA-AVG----QIFFARLSDIFGRFSIMIVSIIFYSMGTI- 151

  Fly   350 LLGNWADRYLPIILLAI-----QLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLLFG 409
                ...:.:.|...|:     ||.|.  |:..:..|::|:.             |.::|.||..
Yeast   152 ----IESQAVNITRFAVGGCFYQLGLT--GIILILEVIASDF-------------SNLNWRLLAL 197

  Fly   410 MIEAF-------------NAVKATIAPGLLLYLWVFAGASIFVGLISL 444
            .|.|.             :|:.|....|:.::.::...|.|.:|:..|
Yeast   198 FIPALPFIINTWISGNVTSAIDANWKWGIGMWAFILPLACIPLGICML 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	48/243 (20%)
SIT1	NP_010849.3	MFS_ARN_like	70..582	CDD:340880	40/207 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900