DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and HXT2

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_013724.1	Gene:	HXT2 / 855023	SGDID:	S000004613	Length:	541	Species:	Saccharomyces cerevisiae

Alignment Length:	479	Identity:	102/479 - (21%)
Similarity:	176/479 - (36%)	Gaps:	83/479 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MCLPKRVGGPAI-QSVATALGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLTGY 64
            :||....||... ....|..|.:...:|...||...:..|.|.|:.||.|           :.|.
Yeast    59 LCLMIAFGGFVFGWDTGTISGFVNQTDFKRRFGQMKSDGTYYLSDVRTGL-----------IVGI 112

  Fly    65 LFLSAALGALVSGFLALKIGPKSVLLCSGLLQISG----------WACIHFGYDIVHIYASRLFA 119
            ..:..|.|.|..|.|....|.:..|:|..|:.|.|          |    :.|     :..|:.:
Yeast   113 FNIGCAFGGLTLGRLGDMYGRRIGLMCVVLVYIVGIVIQIASSDKW----YQY-----FIGRIIS 168

  Fly   120 GVASGAAFVVLPIFINEIAESREKAARLTFTIELWRTLGILIGFV-----------------LGF 167
            |:..|...|:.|..|:|.|....:...::| .:|..||||.:|:.                 ||.
Yeast   169 GMGVGGIAVLSPTLISETAPKHIRGTCVSF-YQLMITLGIFLGYCTNYGTKDYSNSVQWRVPLGL 232

  Fly   168 YVPYAFVNIVGCAVSFVFTMTFPFVQESPHYYLRKNNMASLEKSLRWYRGIRDIDDREKPEYLSE 232
            ...:|...|.|..:          |.|||.:.:.|......::||.....: .|:|   |..::|
Yeast   233 NFAFAIFMIAGMLM----------VPESPRFLVEKGRYEDAKRSLAKSNKV-TIED---PSIVAE 283

  Fly   233 LNEFHAELRSR----DKNVGSTPMSHGYIIRLTFVSFLLTVCAKLSGVFVELNYAADFLGRTGY- 292
            ::...|.:.:.    :.:.|....:.|.|:....:..::....:|:|......|........|.
Yeast   284 MDTIMANVETERLAGNASWGELFSNKGAILPRVIMGIMIQSLQQLTGNNYFFYYGTTIFNAVGMK 348

  Fly   293 -STETNYVVLASAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVIALALFKAYGHLWLLGNWAD 356
             |.:|: :||.....|...:|.....:..|:..|...|   |:..|...:|...|...|..|..|
Yeast   349 DSFQTS-IVLGIVNFASTFVALYTVDKFGRRKCLLGGS---ASMAICFVIFSTVGVTSLYPNGKD 409

  Fly   357 R-------YLPIILLAIQLALVSFGLYPLAAVVSSEVLPTKLHDLLYSLASAVSWLLLFGMIEAF 414
            :       .:.|:...:.:...:....|:|.|:.:|..|.::.:...::|...:|  ::|.:..|
Yeast   410 QPSSKAAGNVMIVFTCLFIFFFAISWAPIAYVIVAESYPLRVKNRAMAIAVGANW--IWGFLIGF 472

  Fly   415 NAVKATIAPGLLLYLWVFAGASIF 438
            .....|.|.| ..|.:||.|..:|
Yeast   473 FTPFITSAIG-FSYGYVFMGCLVF 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	34/164 (21%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	87/421 (21%)
HXT2	NP_013724.1	Sugar_tr	59..519	CDD:395036	102/479 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342358
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740