DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and HXT11

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_014486.1	Gene:	HXT11 / 854009	SGDID:	S000005516	Length:	567	Species:	Saccharomyces cerevisiae

Alignment Length:	503	Identity:	114/503 - (22%)
Similarity:	195/503 - (38%)	Gaps:	123/503 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 ILC-------FNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLT----GYLFLSAALGALV 75
            |||       |.||...|.....:.|.:...|  ..|..| .||.:|:    |.:.....:|..:
Yeast    63 ILCLMIAFGGFIFGWDTGTISGFVNLSDFIRR--FGQKND-KGTYYLSKVRMGLIVSIFNIGCAI 124

  Fly    76 SGFLALKIGP-----------KSVLLCSGLLQISG---WACIHFGYDIVHIYASRLFAGVASGAA 126
            .|.:..|:|.           .::.:...|:||:.   |    :.|     :..|:.:|:..|..
Yeast   125 GGIVLSKVGDIYGRRIGLITVTAIYVVGILIQITSINKW----YQY-----FIGRIISGLGVGGI 180

  Fly   127 FVVLPIFINEIAESREKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNI-------VGCAVSFV 184
            .|:.|:.|:|:|   .|..|.|. ::|::.:|.: |..||:...|...|.       ||..:.|.
Yeast   181 AVLSPMLISEVA---PKHIRGTL-VQLYQLMGTM-GIFLGYCTNYGTKNYHNATQWRVGLGLCFA 240

  Fly   185 FTMTF-----PFVQESPHYYLRKNNMASLEKSLRWYRGIRDIDDREKPEYLSELNEFHAELRSRD 244
            :. ||     .||.|||.|.:........::||.....: .:||   |..|.|.:...|.: ..:
Yeast   241 WA-TFMVSGMMFVPESPRYLIEVGKDEEAKRSLSKSNKV-SVDD---PALLVEYDTIKAGI-ELE 299

  Fly   245 KNVGSTPMSHGYIIRLTFVSFLLTVCAK-----LSGVFVEL-------NYAADFLGRTGY----- 292
            |..|:...|.           ||:...|     |.||.::.       ||.. :.|.|.:
Yeast   300 KLAGNASWSE-----------LLSTKTKVFQRVLMGVMIQSLQQLTGDNYFF-YYGTTIFKSVGL 352

  Fly   293 --STETNYVVLASAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVI-ALALFKAYG--HLWLLG 352
              |.:|: :::.......:.:|.....|..|:  .||  |:.||::: ..|:|.:.|  .||..|
Yeast   353 KDSFQTS-IIIGVVNFFSSFIAVYTIERFGRR--TCL--LWGAASMLCCFAVFASVGVTKLWPQG 412

  Fly   353 NWADRYLPI--------ILLAIQLALVSF------GLYPLAAVVSSEVLPTKLHDLLYSLASAVS 403
            :   .:..|        :::.....:.||      |.|    |:.||..|.::.....::|:|.:
Yeast   413 S---SHQDITSQGAGNCMIVFTMFFIFSFATTWAGGCY----VIVSETFPLRVKSRGMAIATAAN 470

  Fly   404 WLLLFGMIEAFNAVKATIAPGLLLYLWVFAGASIFVGLISLPLLPETR 451
            |  ::|.:.:|.....|.|.. ..|.:||.|..:|........:|||:
Yeast   471 W--MWGFLISFFTPFITGAIN-FYYGYVFLGCLVFAYFYVFFFVPETK 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	37/167 (22%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	102/460 (22%)
HXT11	NP_014486.1	Sugar_tr	64..526	CDD:395036	113/502 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342367
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740