DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG8837 and MAL11

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_011805.3	Gene:	MAL11 / 853207	SGDID:	S000003521	Length:	616	Species:	Saccharomyces cerevisiae

Alignment Length:	484	Identity:	108/484 - (22%)
Similarity:	174/484 - (35%)	Gaps:	121/484 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LGNILCFNFGLMFGITPAHMTLYESEERTPLNQATDPAGTAWLTGYLFLSAALGALVSGFLALKI 83
            :|..:|...|.|.|:   .:|.|..|...  |:.|.......||.|:|:.....:|
Yeast   157 IGLNMCVLCGEMIGL---QITTYMVEFMG--NRYTMITALGLLTAYIFILYYCKSL--------- 207

  Fly    84 GPKSVLLCSGLLQISGWACIHFGYDIVHIYAS-------RLFAGVASGAAFVVLPIFINEIAESR 141
               :::....:|....|.|..   .:...|||       |.:....|...::...||.:.|.::.
Yeast   208 ---AMIAVGQILSAIPWGCFQ---SLAVTYASEVCPLALRYYMTSYSNICWLFGQIFASGIMKNS 266

  Fly   142 EKAARLTFTIELWRTLGILIGFVLGFYVPYAFVNI------VGCAVSFVFTMTFPFVQESPHYYL 200
            ::            .||   ...||:.:|:|...|      :|     :|     |..|||.:.:
Yeast   267 QE------------NLG---NSDLGYKLPFALQWIWPAPLMIG-----IF-----FAPESPWWLV 306

  Fly   201 RKNNMASLEKSL-RWYRGIRDIDDREKPEYLSELNEFHAELR-SRDKNVGSTPMS-----HGYII 258
            ||:.:|...||| |...|.....|.:....|.::     ||. .:::.:.|...|     .|...
Yeast   307 RKDRVAEARKSLSRILSGKGAEKDIQVDLTLKQI-----ELTIEKERLLASKSGSFFNCFKGVNG 366

  Fly   259 RLTFVSFLLTVCAKLSGVFVELNYAADFLGRTGYSTETNYVVLASAQC---AGALLARLVGPRLP 320
            |.|.::.|..|....||. |.|.|:..|..|.|.:|:..:.......|   ||.|.:.::..|:.
Yeast   367 RRTRLACLTWVAQNSSGA-VLLGYSTYFFERAGMATDKAFTFSLIQYCLGLAGTLCSWVISGRVG 430

  Fly   321 RKLLLCLSSLFAAAAVIALALFKAYGHLWLLGNWADRYLPIILLAIQL---ALVSFGLYPLAAVV 382
            |..:|.....|.     .:.||...|..:..|:.|......:|||:..   |.:...:|.:.|.:
Yeast   431 RWTILTYGLAFQ-----MVCLFIIGGMGFGSGSSASNGAGGLLLALSFFYNAGIGAVVYCIVAEI 490

  Fly   383 SSEVLPTK---LHDLLYSLASAVSWLLLFGMIE---------------AFNAVKATIAPGLLLYL 429
            .|..|.||   |..:.|:|.:.::.:|...|:.               .|.||  |:|
Yeast   491 PSAELRTKTIVLARICYNLMAVINAILTPYMLNVSDWNWGAKTGLYWGGFTAV--TLA------- 546

  Fly   430 WVFAGASIFVGLISLPLLPETRNRRPSAV 458
            ||...            ||||..|..|.:
Yeast   547 WVIID------------LPETTGRTFSEI 563

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	25/150 (17%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	96/438 (22%)
MAL11	NP_011805.3	SP	81..563	CDD:273317	108/482 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342345
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.830