Protein Alignment CG8837 and VPS73

DIOPT Version :10

• Sequence 1: NP_608764.1
• Gene: CG8837 / 33545
• FlyBaseID: FBgn0031520
• Length: 485
• Species: Drosophila melanogaster
• Sequence 2: NP_011411.3
• Gene: VPS73 / 852774
• SGDID: S000003072
• Length: 486
• Species: Saccharomyces cerevisiae
• Alignment Length: 522
• Identity: 108/522 - (20%)
• Similarity: 183/522 - (35%)
• Gaps: 124/522 - (23%)

  Fly    12 IQSVATALGNI-------------LCFNF------GLMFG-----ITPAHMTLYESEERTPLNQA 52
            |.|.|:.|.|:             ||:..      .:.||     :......|..||...|:...
Yeast     4 ILSSASLLSNVSMPRQNKHKITKALCYAIIVASIGSIQFGYHLSELNAPQQVLSCSEFDIPMEGY 68

  Fly    53 TDPAGTAWL-------------------TGYLFLSAALGALVSGFLALKIGPKSVLLCSGLLQIS 98
              |....||                   |....:...||:..:..||...|.|...|.:..|.|.
Yeast    69 --PYDRTWLGKRGYKQCIPLNDEQIGIVTSVFCIGGILGSYFATSLANIYGRKFSSLINCTLNIV 131

  Fly    99 GWACIHFGYDIVHIYASRLFAGVASGAAFVVLPIFINEIAESREKAARLTFTIELWRTLGILI-- 161
            |...|........:...|:..|::.|:..|::|:||.|:|.|..:....:.| ::...||:|:
Yeast   132 GSLIIFNSNSYRGLIIGRILVGISCGSLIVIIPLFIKEVAPSGWEGLLGSMT-QICIRLGVLLTQ 195

  Fly   162 GFVLGFYVPYAFVNIV-GCAVSFV-----FTMTFPFVQESPHYYLRKNNMASLEKSLRWYRGIRD 220
            |..|.....|.:..|: |   ||:     |.|.| .|.|||.:.|....:...:.||...||: .
Yeast   196 GIALPLTDSYRWRWILFG---SFLIAVLNFFMWF-IVDESPKWLLAHGRVTDAKLSLCKLRGV-T 255

  Fly   221 IDDREKPEYLSELNEFHAELRSRDKNVGSTPMSH--------GYIIRLTFVSFLLTVCAKLSGVF 277
            .|     |...|:.::..::.|.|..:..|..:.        .|:...|.|        |...|.
Yeast   256 FD-----EAAQEIQDWQLQIESGDPLIEPTTTNSISGSNSLWKYLRDRTNV--------KSRHVI 307

  Fly   278 VELNYAADFLGRTGYSTETNYVVLASAQCAGAL---------------------LARLVGPRLPR 321
            ..|.:...|.|       .|.:||...:....|                     |..|:...|||
Yeast   308 TVLLFGQQFCG-------INSIVLYGTKIISQLYPQHAIRINFFISMVNVLVTILVSLLIHSLPR 365

  Fly   322 KLLLCLSSLFAAAAVIALALFKAYGHLWLLGNWADRYLPIILLAIQLALVSFGLYPLAAVVSSEV 386
            |.||..|::..:.....:.:...:..:.||         |:...|.:.:.:.||.||..::..||
Yeast   366 KPLLMTSTVLVSVTAFIMGIAMNHNKMNLL---------IVFSFIYMGVFTMGLNPLPFIIMREV 421

  Fly   387 LPTKLHDLLYS--LASAVSWLLLFGMIEAFNAVKATIAPGLLLYLWVFAGASIFVGLISLPLLPE 449
              :|..|::.:  ..:..:|:..|.:...|..:...::..:.:   :||..:..:.......:||
Yeast   422 --SKPQDMVLAQRYGTICNWVGTFIIAYTFPIIHDVLSGYVFI---IFAIIACSISAFIWKKVPE 481

  Fly   450 TR 451
            |:
Yeast   482 TK 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_608764.1	MFS_GLUT6_8_Class3_like	15..457	CDD:340916	106/519 (20%)
VPS73	NP_011411.3	MFS_GLUT_Class1_2_like	31..484	CDD:340915	101/495 (20%)