DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG8837 and RGT2

DIOPT Version :9

Sequence 1:	NP_001285582.1	Gene:	CG8837 / 33545	FlyBaseID:	FBgn0031520	Length:	485	Species:	Drosophila melanogaster
Sequence 2:	NP_010143.1	Gene:	RGT2 / 851417	SGDID:	S000002297	Length:	763	Species:	Saccharomyces cerevisiae

Alignment Length:	517	Identity:	101/517 - (19%)
Similarity:	190/517 - (36%)	Gaps:	135/517 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 PAIQSVATALGNILCFNFGLMFG------------------ITPAHMTLYESEERTPLNQATDPA 56
            |...:|.:.|..|.....|.:||                  |.|.|.....|:
Yeast    92 PLRSNVMSVLVGIFVAVGGFLFGYDTGLINSITDMPYVKTYIAPNHSYFTTSQ------------ 144

  Fly    57 GTAWLTGYLFLSAALGALVSGFLALKIGPKSVLLCS--------GLLQISGWACIHFGYDIVHIY 113
             .|.|..:|.|....|||::.:::...|.|..::.|        ..||::...       :|.:.
Yeast   145 -IAILVSFLSLGTFFGALIAPYISDSYGRKPTIMFSTAVIFSIGNSLQVASGG-------LVLLI 201

  Fly   114 ASRLFAGVASGAAFVVLPIFINEIAESREKAARLTFTIELWRTLGILIGFVL-----------GF 167
            ..|:.:|:..|....|:|::..|.|:...:.|.:: :.:...|:|:|:...:           .:
Yeast   202 VGRVISGIGIGIISAVVPLYQAEAAQKNLRGAIIS-SYQWAITIGLLVSSAVSQGTHSKNGPSSY 265

  Fly   168 YVP----YAFVNIVGCAVSFVFTMTFPFVQESPHYYLRKNNMASLEKSLRWYRGIRDIDDREKPE 228
            .:|    |.:.:|:  ||..:      |:.|||.||:.|:.:....|||.:.||: .|:|   |.
Yeast   266 RIPIGLQYVWSSIL--AVGMI------FLPESPRYYVLKDELNKAAKSLSFLRGL-PIED---PR 318

  Fly   229 YLSELNEFHAELRSRDKNVGSTPMSHGY---------IIRLTFVSFLLTVCAKLSGVFVELNYAA 284
            .|.||.|..|.. ..:.:.|.:.:...:         |:|: |....:....:.||:.....|..
Yeast   319 LLEELVEIKATY-DYEASFGPSTLLDCFKTSENRPKQILRI-FTGIAIQAFQQASGINFIFYYGV 381

  Fly   285 DFLGRTGYSTE-----TNYVVLASAQCAGALLARLVGPRLPRKLLLCLSSLFAAAAVIALALFKA 344
            :|...||....     .:|.|..:....|..|...:|    |:.:|....:..|.|.:.:|
Yeast   382 NFFNNTGVDNSYLVSFISYAVNVAFSIPGMYLVDRIG----RRPVLLAGGVIMAIANLVIA---- 438

  Fly   345 YGHLWLLGNWADRYLPIILLAIQLALVSFGLYPLAA-------VVSSEVLPTKLHDLLYSLASAV 402
                 ::|  ......::...|.:|.:...:...:|       |||:|:.|..:.....::.:|.
Yeast   439 -----IVG--VSEGKTVVASKIMIAFICLFIAAFSATWGGVVWVVSAELYPLGVRSKCTAICAAA 496

  Fly   403 SWLLLFGMIEAFNAVKATIAPGL-------------LLYLWVFAGASIFVGLISLPLLPETR 451
            :||:        |...|.|.|.:             :.::|  .|.::...::....:.|||
Yeast   497 NWLV--------NFTCALITPYIVDVGSHTSSMGPKIFFIW--GGLNVVAVIVVYFAVYETR 548

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG8837	NP_001285582.1	MFS	54..>192	CDD:119392	29/160 (18%)
CG8837	NP_001285582.1	Sugar_tr	58..453	CDD:278511	90/451 (20%)
RGT2	NP_010143.1	SP	76..555	CDD:273317	101/517 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157342336
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0254
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740